integrin alpha V

Synonym

2610028E01Rik, CD51, alphav-integrin, Itgav, Integrin alpha-V precursor, Vitronectin receptor subunit alpha, vitronectin receptor alpha polypeptide (VNRA), integrin alpha V, 1110004F14Rik, CD51 antigen

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:9.90

cerebellum:8.87

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:9.33

spine:10.02

retina:10.75

eye:10.60

artery/aorta:-

vein:11.20

lymphnode:9.42

peripheral blood:-

spleen:9.07

thymus:-

bone marrow:8.58

adipose:9.43

bone:9.59

skin:10.69

CAGE

cerebrum:3.44

cerebellum:-

brain stem:3.95

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.40

retina:-

eye:-

artery/aorta:3.86

vein:-

lymphnode:3.88

peripheral blood:-

spleen:3.28

thymus:3.37

bone marrow:-

adipose:-

bone:3.64

skin:4.04

RNA-seq

cerebrum:2.28

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:10.57

placenta:11.39

prostate:9.73

ovary:10.92

testis:6.45

heart:8.83

muscle:9.54

esophagus:-

stomach:10.15

intestine:9.52

colon:-

liver/hepato:8.93

lung:9.84

bladder:10.61

kidney:10.81

pituitary:9

thyroid/parathyroid:-

adrenal gland:10.75

pancreas:8.66

breast:9.93

salivary:10.32

CAGE

uterus:4.61

placenta:5.14

prostate:4.06

ovary:4.61

testis:2.05

heart:-

muscle:-

esophagus:-

stomach:3.72

intestine:3.33

colon:3.41

liver/hepato:3.66

lung:3.91

bladder:4.25

kidney:-

pituitary:3.17

thyroid/parathyroid:-

adrenal gland:4.20

pancreas:3.45

breast:4.21

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:2.42

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.85

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008402
Gene ID	16410
Unigene ID	-
Probe set ID	1452784_at [Mouse430_2]
Ensembl ID	ENSMUSG00000027087

Orthologous Gene

Human[3]	NM_001144999, NM_001145000, NM_002210
Rat[3]	NM_001144999, NM_001145000, NM_002210

Chromosomal Region

Gene Family (Interpro ID)

IPR013517	FG-GAP
IPR013519	Integrin alpha beta-propellor

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0043277	apoptotic cell clearance
GO:0001568	blood vessel development
GO:0070588	calcium ion transmembrane transport
GO:0007155	cell adhesion
GO:0030154	cell differentiation
GO:0016477	cell migration
GO:0007160	cell-matrix adhesion
GO:0006874	cellular calcium ion homeostasis
GO:0032490	detection of molecule of bacterial origin
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0043542	endothelial cell migration
GO:0070371	ERK1 and ERK2 cascade
GO:0009566	fertilization
GO:0048041	focal adhesion formation
GO:0035262	gonad morphogenesis
GO:0006954	inflammatory response
GO:0007229	integrin-mediated signaling pathway
GO:0007275	multicellular organismal development
GO:0010888	negative regulation of lipid storage
GO:0032369	negative regulation of lipid transport
GO:0050748	negative regulation of lipoprotein metabolic process
GO:0045715	negative regulation of low-density lipoprotein receptor biosynthetic process
GO:0010745	negative regulation of macrophage derived foam cell differentiation
GO:0045785	positive regulation of cell adhesion
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0043410	positive regulation of MAPKKK cascade
GO:0033690	positive regulation of osteoblast proliferation
GO:0045124	regulation of bone resorption
GO:0050764	regulation of phagocytosis
GO:0051209	release of sequestered calcium ion into cytosol
GO:0042110	T cell activation
GO:0060707	trophoblast giant cell differentiation

Cellular Component

GO:0034683	alphav-beta3 integrin complex
GO:0009986	cell surface
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0008305	integrin complex
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0031994	insulin-like growth factor I binding
GO:0046872	metal ion binding
GO:0001846	opsonin binding
GO:0042277	peptide binding
GO:0046982	protein heterodimerization activity
GO:0005080	protein kinase C binding
GO:0005102	receptor binding
GO:0005245	voltage-gated calcium channel activity

integrin alpha V

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function