annexin A1

 jump to detail

Synonym

Lipocortin I, Lpc-1, Anxa1, Annexin A1, Anx-1, Annexin I, Calpactin II, Chromobindin-9, Anx1, Anx-A1, Phospholipase A2 inhibitory protein, annexin A1, Lpc1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:76.40 spine:- retina:- eye:91.20 artery/aorta:- vein:- lymphnode:421.30 peripheral blood:244.40 spleen:131.70 thymus:138.30 bone marrow:1679.60 adipose:425.40 bone:413.30 skin:4323
GeneChip cerebrum:6.27 cerebellum:5.27 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.22 spine:5.78 retina:9.71 eye:12.13 artery/aorta:- vein:13.79 lymphnode:10.25 peripheral blood:- spleen:9.65 thymus:- bone marrow:13.32 adipose:11.38 bone:13.48 skin:13.41
CAGE cerebrum:0.99 cerebellum:- brain stem:1.42 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.17 retina:- eye:- artery/aorta:4.68 vein:- lymphnode:3.62 peripheral blood:- spleen:4.88 thymus:3.24 bone marrow:- adipose:- bone:6.44 skin:5.83
RNA-seq cerebrum:1.75 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:745.60 prostate:339.70 ovary:11.50 testis:110.80 heart:74.40 muscle:745.70 esophagus:- stomach:490.90 intestine:37 colon:52.90     liver/hepato:27.20        lung:411.70    bladder:66.20 kidney:32.20 pituitary:25.80 thyroid/parathyroid:1462.20 adrenal gland:- pancreas:46.90 breast:538.70 salivary:-
GeneChip uterus:12.71 placenta:12.47 prostate:12.42 ovary:11.62 testis:6.18 heart:9.55 muscle:9.75 esophagus:- stomach:11.14 intestine:9.95 colon:- liver/hepato:7.50 lung:12.15 bladder:11.63 kidney:8 pituitary:6.14 thyroid/parathyroid:- adrenal gland:8.27 pancreas:9.02 breast:11.48 salivary:11.37
CAGE uterus:5.86 placenta:5.68 prostate:3.63 ovary:4.65 testis:1.18 heart:- muscle:- esophagus:- stomach:4.98 intestine:2.58 colon:2.88     liver/hepato:1.94    lung:5.63 bladder:4.85 kidney:- pituitary:2.35 thyroid/parathyroid:- adrenal gland:3.56 pancreas:3.27 breast:4.11 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:7.38 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.31        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_010730
Gene ID 16952
Unigene ID Mm.248360
Probe set ID 1448213_at  [Mouse430_2]
Ensembl ID ENSMUSG00000024659

Orthologous Gene

Human[1]  NM_000700
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001464  Annexin
IPR002388  Annexin, type I

Link to Pubmed  (Pubmed ID)

1676980
2522299
2974946
7592984
7698766
7706559
7768185
7774911
7782070
7894166
8013374
8043949
8075499
8499657
8587144
8634333
8719346
9107690
9525630
9606417
9624122
9763662
9826670
9924185
10349636
10725249
10876093
10922068
10956639
11042159
11076861
11217851
11423996
11440986
11741941
12466851
12475898
12477932
12516535
12553880
12560218
12586783
14506282
14967753
15022342
15064349
15169834
15197108
15485879
15489334
15556938
15749912
15920146
16000391
16014420
16141072
16141073
16210453
16547279
16601136
16602821
16720734
16829211
16835395
17008549
17026533
17114490
17158208
17218541
17405164
17948261
18056401
18081892
18469846
18794802
18802107
18827967
18952200
19029200
19095957
19103997
19104500
19208747
19244132
19553536
19625660
19805119
19912648
20139728
20308542
20489160
20558817
20578244
20821804
20962261
21245195
21267068
21370880
21383699
21398608
21565611
21677750
21957127
22011168
22092555
22493082
22511458
22539796
22562975
22673621
22791338
22964301
23038751
23077482
23241962
23267026
23277424
23277546
23638088
23645879
23777345
24048896
24187664
24312665
24648446

Gene Ontology  (GO ID)

Biological Process

GO:0046632  alpha-beta T cell differentiation
GO:0050482  arachidonic acid secretion
GO:0007166  cell surface receptor linked signal transduction
GO:0071385  cellular response to glucocorticoid stimulus
GO:0070301  cellular response to hydrogen peroxide
GO:0030073  insulin secretion
GO:0030216  keratinocyte differentiation
GO:0002674  negative regulation of acute inflammatory response
GO:0043066  negative regulation of apoptosis
GO:0043086  negative regulation of catalytic activity
GO:0050709  negative regulation of protein secretion
GO:0001780  neutrophil homeostasis
GO:0018149  peptide cross-linking
GO:0043065  positive regulation of apoptosis
GO:0033031  positive regulation of neutrophil apoptosis
GO:0031394  positive regulation of prostaglandin biosynthetic process
GO:0031340  positive regulation of vesicle fusion
GO:0042127  regulation of cell proliferation
GO:0007165  signal transduction

Cellular Component

GO:0042995  cell projection
GO:0005929  cilium
GO:0001533  cornified envelope
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0070062  extracellular vesicular exosome
GO:0016020  membrane
GO:0031966  mitochondrial membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0042383  sarcolemma

Molecular Function

GO:0005509  calcium ion binding
GO:0005544  calcium-dependent phospholipid binding
GO:0019834  phospholipase A2 inhibitor activity
GO:0004859  phospholipase inhibitor activity
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0030674  protein binding, bridging
GO:0042803  protein homodimerization activity
GO:0003697  single-stranded DNA binding
GO:0003727  single-stranded RNA binding
GO:0005198  structural molecule activity