mannan-binding lectin serine peptidase 1

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Synonym

Masp1/3, Crarf, mannan-binding lectin serine peptidase 1, Ra-reactive factor serine protease p100, Mannan-binding lectin serine protease 1, Masp1, CCPII, RaRF, AW048060

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13.90 cerebellum:55.30 brain stem:95.30 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:38 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:- spleen:- thymus:9.90 bone marrow:12.80 adipose:- bone:- skin:79.20
GeneChip cerebrum:4.19 cerebellum:4.14 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.14 spine:4.25 retina:4.43 eye:4.65 artery/aorta:- vein:4.15 lymphnode:4.01 peripheral blood:- spleen:4.14 thymus:- bone marrow:3.93 adipose:4.10 bone:4.17 skin:4.05
CAGE cerebrum:2.20 cerebellum:- brain stem:2.64 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.09 retina:- eye:- artery/aorta:1.28 vein:- lymphnode:0.42 peripheral blood:- spleen:0.16 thymus:0.27 bone marrow:- adipose:- bone:0.63 skin:2.09
RNA-seq cerebrum:2.68 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:91.90 testis:7.40 heart:18.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:10    bladder:- kidney:80.60 pituitary:51.70 thyroid/parathyroid:- adrenal gland:424.40 pancreas:- breast:62 salivary:54
GeneChip uterus:4.03 placenta:4.32 prostate:4.10 ovary:4.21 testis:4.31 heart:4.51 muscle:4.32 esophagus:- stomach:4.13 intestine:4.04 colon:- liver/hepato:9.89 lung:4.58 bladder:3.95 kidney:4.05 pituitary:4.17 thyroid/parathyroid:- adrenal gland:4.11 pancreas:4.64 breast:4.15 salivary:4.55
CAGE uterus:1.32 placenta:4.73 prostate:3.11 ovary:2.93 testis:0.45 heart:- muscle:- esophagus:- stomach:1.35 intestine:0.72 colon:0.70     liver/hepato:5.27    lung:1.62 bladder:1.14 kidney:- pituitary:1.86 thyroid/parathyroid:- adrenal gland:2.66 pancreas:1.30 breast:0.22 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.55 esophagus:- stomach:- intestine:- colon:-     liver/hepato:8.64        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_008555
Gene ID 17174
Unigene ID Mm.121361
Probe set ID 1419677_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022887

Orthologous Gene

Human[4]  NM_001031849, NM_001879, NM_139125
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3
IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like
IPR000436  Sushi/SCR/CCP

Link to Pubmed  (Pubmed ID)

7759119
8133044
8439319
8889548
9794427
10349636
10700458
11042159
11076861
11217851
12466851
12477932
12847554
15950722
16141072
16141073
17182967
18424734
20038603
20152175
20399528
20870940
21267068
21865552
21943708
22156595
23650618
24279761

Gene Ontology  (GO ID)

Biological Process

GO:0006956  complement activation
GO:0001867  complement activation, lectin pathway
GO:0045087  innate immune response
GO:0008152  metabolic process
GO:0006508  proteolysis

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0005509  calcium ion binding
GO:0048306  calcium-dependent protein binding
GO:0003824  catalytic activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0008233  peptidase activity
GO:0042803  protein homodimerization activity
GO:0004252  serine-type endopeptidase activity
GO:0008236  serine-type peptidase activity