homeobox, msh-like 2

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Synonym

Msx-2, BB122635, Hox8, Msx2, Homeobox protein MSX-2, homeo box, msh-like 2, Hox-8, Hox-8.1, Hox8.1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:85.10

cerebellum:257.90

brain stem:127.10

corpus callosum/glia:-

pineal gland:-

peripheral nerve:95.50

spine:331

retina:-

eye:45.60

artery/aorta:84.40

vein:-

lymphnode:64.80

peripheral blood:57.50

spleen:-

thymus:59.30

bone marrow:-

adipose:-

bone:25

skin:79.20

GeneChip

cerebrum:4.85

cerebellum:5.71

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5

spine:5.12

retina:4.76

eye:5.60

artery/aorta:-

vein:6.60

lymphnode:4.70

peripheral blood:-

spleen:4.79

thymus:-

bone marrow:4.96

adipose:4.87

bone:4.83

skin:5.62

CAGE

cerebrum:1.77

cerebellum:-

brain stem:0.62

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.11

retina:-

eye:-

artery/aorta:0.14

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:-

bone:0

skin:5.19

RNA-seq

cerebrum:0.98

cerebellum:0.98

brain stem:0.98

corpus callosum/glia:0.98

pineal gland:0.98

peripheral nerve:0.98

spine:0.98

retina:0.98

eye:0.98

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:-

prostate:-

ovary:34.50

testis:36.90

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:130.50

bladder:264.70

kidney:16.10

pituitary:51.70

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:35.90

salivary:-

GeneChip

uterus:6.45

placenta:6.86

prostate:5.03

ovary:5.05

testis:4.87

heart:5.38

muscle:4.88

esophagus:-

stomach:4.87

intestine:4.89

colon:-

liver/hepato:5.22

lung:4.65

bladder:7.88

kidney:5.01

pituitary:4.98

thyroid/parathyroid:-

adrenal gland:4.83

pancreas:5.79

breast:5.43

salivary:5.48

CAGE

uterus:3.30

placenta:2.86

prostate:0.63

ovary:1.76

testis:0

heart:-

muscle:-

esophagus:-

stomach:1.07

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:4.21

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:1.22

pancreas:0

breast:0.43

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_013601
Gene ID	17702
Unigene ID	Mm.17631
Probe set ID	1449559_at [Mouse430_2]
Ensembl ID	ENSMUSG00000021469

Orthologous Gene

Human[2]	NM_002449
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Gene Ontology (GO ID)

Biological Process

GO:0042640	anagen
GO:0009952	anterior/posterior pattern formation
GO:0030509	BMP signaling pathway
GO:0060349	bone morphogenesis
GO:0060346	bone trabecula formation
GO:0060444	branching involved in mammary gland duct morphogenesis
GO:0051216	cartilage development
GO:0071392	cellular response to estradiol stimulus
GO:0071363	cellular response to growth factor stimulus
GO:0002063	chondrocyte development
GO:0042733	embryonic digit morphogenesis
GO:0035115	embryonic forelimb morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0030326	embryonic limb morphogenesis
GO:0070166	enamel mineralization
GO:0003416	endochondral bone growth
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0060364	frontal suture morphogenesis
GO:0007275	multicellular organismal development
GO:0043066	negative regulation of apoptosis
GO:0008285	negative regulation of cell proliferation
GO:0032792	negative regulation of CREB transcription factor activity
GO:0045599	negative regulation of fat cell differentiation
GO:0045617	negative regulation of keratinocyte differentiation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0042476	odontogenesis
GO:0001503	ossification
GO:0002076	osteoblast development
GO:0001649	osteoblast differentiation
GO:0003151	outflow tract morphogenesis
GO:0003148	outflow tract septum morphogenesis
GO:0043065	positive regulation of apoptosis
GO:0030513	positive regulation of BMP signaling pathway
GO:0051795	positive regulation of catagen
GO:0045669	positive regulation of osteoblast differentiation
GO:0042981	regulation of apoptosis
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0048863	stem cell differentiation
GO:0006366	transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent
GO:0042060	wound healing
GO:0035313	wound healing, spreading of epidermal cells

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0003712	transcription cofactor activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

homeobox, msh-like 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function