myosin IXb

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Synonym

Unconventional myosin-9b, Myosin-9B, Myosin IXb, Myr5, myosin IXb, Myo9b

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.57 cerebellum:7.56 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.76 spine:7.59 retina:7.22 eye:7.82 artery/aorta:- vein:8.37 lymphnode:9.31 peripheral blood:- spleen:9.30 thymus:- bone marrow:8.76 adipose:7.34 bone:8.65 skin:7.87
CAGE cerebrum:2.94 cerebellum:- brain stem:2.82 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.94 retina:- eye:- artery/aorta:2.98 vein:- lymphnode:3.75 peripheral blood:- spleen:3.18 thymus:3.49 bone marrow:- adipose:- bone:3.35 skin:3.27
RNA-seq cerebrum:3.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:8.57 placenta:8.08 prostate:7.94 ovary:8.03 testis:6.97 heart:7.55 muscle:7.24 esophagus:- stomach:7.63 intestine:7.78 colon:- liver/hepato:7.33 lung:8.19 bladder:8.05 kidney:7.07 pituitary:8.48 thyroid/parathyroid:- adrenal gland:7.98 pancreas:7.98 breast:7.85 salivary:8.52
CAGE uterus:3.25 placenta:3.04 prostate:2.19 ovary:3.23 testis:2.41 heart:- muscle:- esophagus:- stomach:1.75 intestine:2.35 colon:2.53     liver/hepato:2.41    lung:3.15 bladder:3.10 kidney:- pituitary:3.34 thyroid/parathyroid:- adrenal gland:3.22 pancreas:2.56 breast:2.77 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.23 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.15        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001142322
Gene ID 17925
Unigene ID Mm.337795
Probe set ID 1418031_at  [Mouse430_2]
Ensembl ID ENSMUSG00000004677

Orthologous Gene

Human[5]  NM_001130065, NM_004145
Rat[1]  NM_012984, NM_004145

Chromosomal Region

8B3.3  [73,796,613  -  73,884,611]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

8884266
8954808
9169155
9417917
10349636
10580159
10729222
11042159
11076861
11212352
11217851
12466851
12477932
12520002
15782199
16141072
16141073
17314409
20566876
21267068
21677750
23649778
24646736

Gene Ontology  (GO ID)

Biological Process

GO:0033275  actin-myosin filament sliding
GO:0006200  ATP catabolic process
GO:0030010  establishment of cell polarity
GO:0048246  macrophage chemotaxis
GO:0002548  monocyte chemotaxis
GO:0032321  positive regulation of Rho GTPase activity
GO:0007266  Rho protein signal transduction
GO:0007165  signal transduction

Cellular Component

GO:0005884  actin filament
GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0031941  filamentous actin
GO:0032433  filopodium tip
GO:0005622  intracellular
GO:0030027  lamellipodium
GO:0016459  myosin complex
GO:0048471  perinuclear region of cytoplasm
GO:0001726  ruffle

Molecular Function

GO:0003779  actin binding
GO:0051015  actin filament binding
GO:0030898  actin-dependent ATPase activity
GO:0043531  ADP binding
GO:0005524  ATP binding
GO:0043008  ATP-dependent protein binding
GO:0016887  ATPase activity
GO:0005516  calmodulin binding
GO:0005096  GTPase activator activity
GO:0046872  metal ion binding
GO:0000146  microfilament motor activity
GO:0003774  motor activity
GO:0000166  nucleotide binding
GO:0005100  Rho GTPase activator activity
GO:0008270  zinc ion binding