nuclear receptor coactivator 1

Synonym

Steroid receptor coactivator 1, steroid receptor coactivator-1, SRC-a/NCoA-1, nuclear receptor coactivator 1, Nuclear receptor coactivator 1, NCoA-1, Ncoa1, SRC-1, SRC1, mNRC-1, MGC90703, Nuclear receptor coactivator protein 1, Src1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:62.50

cerebellum:36.80

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:64.30

eye:114

artery/aorta:-

vein:-

lymphnode:75.60

peripheral blood:-

spleen:52.70

thymus:9.90

bone marrow:-

adipose:212.70

bone:37.60

skin:63.30

GeneChip

cerebrum:9.42

cerebellum:9.72

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.75

spine:8.91

retina:9.90

eye:8.71

artery/aorta:-

vein:7.49

lymphnode:8.13

peripheral blood:-

spleen:8.27

thymus:-

bone marrow:7.93

adipose:8.35

bone:7.89

skin:8.43

CAGE

cerebrum:3.74

cerebellum:-

brain stem:3.26

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.44

retina:-

eye:-

artery/aorta:3.04

vein:-

lymphnode:3.16

peripheral blood:-

spleen:2.49

thymus:2.44

bone marrow:-

adipose:-

bone:2.09

skin:3.53

RNA-seq

cerebrum:6.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:11.50

testis:14.80

heart:18.60

muscle:-

esophagus:-

stomach:-

intestine:-

colon:17.60

liver/hepato:9.10

lung:10

bladder:-

kidney:24.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:37.50

breast:42.40

salivary:-

GeneChip

uterus:7.99

placenta:6.06

prostate:8.41

ovary:8.11

testis:7.47

heart:8.40

muscle:8.53

esophagus:-

stomach:8.05

intestine:8.33

colon:-

liver/hepato:7.52

lung:8.44

bladder:8.12

kidney:8.23

pituitary:8.95

thyroid/parathyroid:-

adrenal gland:8.72

pancreas:8.53

breast:7.96

salivary:8.80

CAGE

uterus:2.64

placenta:1.30

prostate:3.28

ovary:2.75

testis:1.34

heart:-

muscle:-

esophagus:-

stomach:1.91

intestine:2.27

colon:2.84

liver/hepato:2.70

lung:3.16

bladder:2.79

kidney:-

pituitary:3.34

thyroid/parathyroid:-

adrenal gland:3.11

pancreas:3.32

breast:2.87

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.97

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.10

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010881
Gene ID	17977
Unigene ID	Mm.301039
Probe set ID	1418594_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000020647

Orthologous Gene

Human[12]	NM_003743, NM_147223, NM_147233
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000014

PAS

Gene Ontology (GO ID)

Biological Process

GO:0032870	cellular response to hormone stimulus
GO:0043967	histone H4 acetylation
GO:0060713	labyrinthine layer morphogenesis
GO:0060179	male mating behavior
GO:0043065	positive regulation of apoptosis
GO:0045925	positive regulation of female receptivity
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0000435	positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006355	regulation of transcription, DNA-dependent
GO:0032355	response to estradiol stimulus
GO:0032570	response to progesterone stimulus
GO:0032526	response to retinoic acid
GO:0007165	signal transduction
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0043005	neuron projection
GO:0000790	nuclear chromatin
GO:0005634	nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0019899	enzyme binding
GO:0030331	estrogen receptor binding
GO:0004402	histone acetyltransferase activity
GO:0016922	ligand-dependent nuclear receptor binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257	nuclear hormone receptor binding
GO:0033142	progesterone receptor binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0046983	protein dimerization activity
GO:0047485	protein N-terminus binding
GO:0042974	retinoic acid receptor binding
GO:0046965	retinoid X receptor binding
GO:0004871	signal transducer activity
GO:0003713	transcription coactivator activity
GO:0008134	transcription factor binding
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups

nuclear receptor coactivator 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function