neurexin I

 jump to detail

Synonym

mKIAA0578, Nrxn1, A230068P09Rik, 9330127H16Rik, alpha-latrotoxin receptor (calcium-dependent), neurexin I alpha, Kiaa0578, Neurexin I-alpha, neurexin I, neurexin I beta, Neurexin-1-alpha precursor, 1700062G21Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:36.80 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:6.47 cerebellum:- brain stem:5.84 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.58 retina:- eye:- artery/aorta:0.14 vein:- lymphnode:2.28 peripheral blood:- spleen:0.62 thymus:0.49 bone marrow:- adipose:- bone:0 skin:0.84
RNA-seq cerebrum:8.34 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0.31 placenta:0.20 prostate:1.73 ovary:1.14 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:0 colon:0.70     liver/hepato:2.76    lung:0.91 bladder:1.62 kidney:- pituitary:5.43 thyroid/parathyroid:- adrenal gland:3.57 pancreas:0.84 breast:0.50 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.60        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_020252
Gene ID 18189
Unigene ID Mm.461950
Probe set ID -
Ensembl ID ENSMUSG00000024109

Orthologous Gene

Human[9]  NM_001135659, NM_004801, NM_138735
Rat[9]  NM_001135659, NM_004801, NM_138735

Chromosomal Region

17E5  [90,435,914  -  91,492,337]

Gene Family (Interpro ID)

IPR008985  Concanavalin A-like lectin/glucanase
IPR013320  Concanavalin A-like lectin/glucanase, subgroup
IPR000742  EGF-like, type 3
IPR001791  Laminin G

Link to Pubmed  (Pubmed ID)

7722633
8889548
9223334
9430716
9448462
10349636
10408888
11042159
11076861
11171101
11217851
11243866
11741895
12036300
12465718
12466851
12477932
12796785
12827191
14522992
14983056
15489334
15620359
15858059
16141072
16141073
16186258
16406382
16602821
16919269
16987237
17035546
17347997
18799693
19036990
19098102
19567877
19816407
19822762
19926856
20537373
20869594
21149722
21262241
21267068
21356198
21410790
21424692
21559374
21677750
22196734
22235116
22348092
22457515
22832527
23141067
23840597
23875667
24094106

Gene Ontology  (GO ID)

Biological Process

GO:0030534  adult behavior
GO:0001525  angiogenesis
GO:0016339  calcium-dependent cell-cell adhesion
GO:0007155  cell adhesion
GO:0045184  establishment of protein localization
GO:0060325  face morphogenesis
GO:0007157  heterophilic cell adhesion
GO:0007612  learning
GO:0051490  negative regulation of filopodium assembly
GO:0050885  neuromuscular process controlling balance
GO:0007158  neuron adhesion
GO:0007269  neurotransmitter secretion
GO:0043473  pigmentation
GO:0090004  positive regulation of establishment of protein localization in plasma membrane
GO:0090129  positive regulation of synapse maturation
GO:0051968  positive regulation of synaptic transmission, glutamatergic
GO:0051965  positive regulation of synaptogenesis
GO:0060134  prepulse inhibition
GO:0051290  protein heterotetramerization
GO:0035176  social behavior
GO:0007416  synapse assembly
GO:0007268  synaptic transmission

Cellular Component

GO:0005623  cell
GO:0030054  cell junction
GO:0009986  cell surface
GO:0030139  endocytic vesicle
GO:0060076  excitatory synapse
GO:0060077  inhibitory synapse
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0042734  presynaptic membrane
GO:0045202  synapse

Molecular Function

GO:0033130  acetylcholine receptor binding
GO:0005246  calcium channel regulator activity
GO:0005509  calcium ion binding
GO:0048306  calcium-dependent protein binding
GO:0050839  cell adhesion molecule binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0005102  receptor binding