sequestosome 1

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Synonym

Sequestosome-1, A170, Osi, Sqstm1, Ubiquitin-binding protein p62, STAP, OSF-6, sequestosome 1, STONE14

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:6.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:-

retina:-

eye:7.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:14.40

spleen:13.20

thymus:9.90

bone marrow:-

adipose:-

bone:37.60

skin:-

GeneChip

cerebrum:11.76

cerebellum:11.34

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:12.36

spine:11.87

retina:8.79

eye:9.28

artery/aorta:-

vein:10.46

lymphnode:11.25

peripheral blood:-

spleen:10.76

thymus:-

bone marrow:10.71

adipose:11.38

bone:10.33

skin:10.20

CAGE

cerebrum:5.46

cerebellum:-

brain stem:6.01

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:6.02

retina:-

eye:-

artery/aorta:5.17

vein:-

lymphnode:4.15

peripheral blood:-

spleen:5.08

thymus:4.73

bone marrow:-

adipose:-

bone:4.67

skin:5.32

RNA-seq

cerebrum:112.98

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:41.40

prostate:-

ovary:-

testis:7.40

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:30.10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:-

breast:9.80

salivary:-

GeneChip

uterus:11.67

placenta:12.07

prostate:11.82

ovary:12.11

testis:9.51

heart:11.08

muscle:12.15

esophagus:-

stomach:11.07

intestine:11.04

colon:-

liver/hepato:11.98

lung:11.83

bladder:11.76

kidney:12.12

pituitary:11.98

thyroid/parathyroid:-

adrenal gland:11.93

pancreas:10.90

breast:11.22

salivary:10.42

CAGE

uterus:5.44

placenta:6.18

prostate:6.00

ovary:5.76

testis:4.61

heart:-

muscle:-

esophagus:-

stomach:5.45

intestine:4.75

colon:5.25

liver/hepato:6.02

lung:5.68

bladder:5.94

kidney:-

pituitary:5.93

thyroid/parathyroid:-

adrenal gland:6.31

pancreas:5.90

breast:5.08

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:154.54

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:98.74

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_011018
Gene ID	18412
Unigene ID	Mm.40828
Probe set ID	1450957_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000015837

Orthologous Gene

Human[6]	NM_001142298, NM_001142299, NM_003900
Rat[1]	NM_175843, NM_001142299, NM_003900

Chromosomal Region

Gene Family (Interpro ID)

IPR000449	Ubiquitin-associated/translation elongation factor EF1B, N-terminal
IPR015940	Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0006914	autophagy
GO:0030154	cell differentiation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade

Cellular Component

GO:0016235	aggresome
GO:0005776	autophagic vacuole
GO:0005737	cytoplasm
GO:0000932	cytoplasmic mRNA processing body
GO:0031410	cytoplasmic vesicle
GO:0005783	endoplasmic reticulum
GO:0005768	endosome
GO:0005764	lysosome
GO:0005634	nucleus
GO:0000407	pre-autophagosomal structure

Molecular Function

GO:0042802	identical protein binding
GO:0070530	K63-linked polyubiquitin binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0005080	protein kinase C binding
GO:0042169	SH2 domain binding
GO:0003712	transcription cofactor activity
GO:0043130	ubiquitin binding
GO:0008270	zinc ion binding

sequestosome 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function