parathyroid hormone 1 receptor

Synonym

PTH-related peptide receptor, PTH/PTHrP type I receptor, parathyroid hormone receptor 1, PPR, Pthr, PTH1R, PTH/PTHr receptor, Pthr1, PTH/PTHrP receptor

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.67

cerebellum:6.53

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.91

spine:6.90

retina:4.92

eye:5.66

artery/aorta:-

vein:8.37

lymphnode:5.17

peripheral blood:-

spleen:5.77

thymus:-

bone marrow:5.22

adipose:7.17

bone:7.93

skin:5.84

CAGE

cerebrum:1.26

cerebellum:-

brain stem:1.78

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.82

retina:-

eye:-

artery/aorta:2.18

vein:-

lymphnode:0.42

peripheral blood:-

spleen:0.86

thymus:0.27

bone marrow:-

adipose:-

bone:3.14

skin:2.03

RNA-seq

cerebrum:1.90

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:30.90

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:9.22

placenta:8.75

prostate:5.26

ovary:7.65

testis:5.03

heart:6.14

muscle:5.80

esophagus:-

stomach:5.64

intestine:5.90

colon:-

liver/hepato:7.02

lung:5.53

bladder:7.07

kidney:11.91

pituitary:5.20

thyroid/parathyroid:-

adrenal gland:7.04

pancreas:5.06

breast:6.73

salivary:5.78

CAGE

uterus:3.36

placenta:3.45

prostate:0.63

ovary:2.13

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0.72

colon:0.57

liver/hepato:2.76

lung:0.55

bladder:2.29

kidney:-

pituitary:0.29

thyroid/parathyroid:-

adrenal gland:1.94

pancreas:0

breast:1.20

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.32

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.60

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001083936
Gene ID	19228
Unigene ID	Mm.354224
Probe set ID	1417092_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032492

Orthologous Gene

Human[1]	NM_000316, NM_001184744
Rat [0]

Chromosomal Region

9F2 [110,624,592 - 110,649,649]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000832	GPCR, family 2, secretin-like
IPR017981	GPCR, family 2-like

Gene Ontology (GO ID)

Biological Process

GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0030282	bone mineralization
GO:0045453	bone resorption
GO:0048469	cell maturation
GO:0007166	cell surface receptor linked signal transduction
GO:0006874	cellular calcium ion homeostasis
GO:0002062	chondrocyte differentiation
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0008285	negative regulation of cell proliferation
GO:0001503	ossification
GO:0002076	osteoblast development
GO:0008284	positive regulation of cell proliferation
GO:0060732	positive regulation of inositol phosphate biosynthetic process
GO:0007165	signal transduction
GO:0001501	skeletal system development

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0031526	brush border membrane
GO:0005737	cytoplasm
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0005622	intracellular
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043235	receptor complex

Molecular Function

GO:0004930	G-protein coupled receptor activity
GO:0004991	parathyroid hormone receptor activity
GO:0017046	peptide hormone binding
GO:0043621	protein self-association
GO:0004871	signal transducer activity
GO:0004888	transmembrane receptor activity

parathyroid hormone 1 receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function