dual specificity phosphatase 1

Synonym

Ptpn10, Protein-tyrosine phosphatase 3CH134, MKP-1, MAP kinase phosphatase 1, dual specificity phosphatase 1, mkp-1, Protein-tyrosine phosphatase ERP, Ptpn16, erp, Dual specificity protein phosphatase 1, U19515, 3ch134, Dusp1, 3CH134, Mkp1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:9.63

cerebellum:10.48

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:9.20

spine:8.54

retina:7.92

eye:8.72

artery/aorta:-

vein:10.70

lymphnode:8.94

peripheral blood:-

spleen:9.44

thymus:-

bone marrow:10.17

adipose:10.11

bone:9.96

skin:11.06

CAGE

cerebrum:3.18

cerebellum:-

brain stem:2.90

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.84

retina:-

eye:-

artery/aorta:4.26

vein:-

lymphnode:3.87

peripheral blood:-

spleen:3.24

thymus:2.32

bone marrow:-

adipose:-

bone:3.54

skin:4.40

RNA-seq

cerebrum:7.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:9.09

placenta:10.24

prostate:8.69

ovary:10.08

testis:7.67

heart:10.87

muscle:10.48

esophagus:-

stomach:8.98

intestine:8.89

colon:-

liver/hepato:9.72

lung:12.68

bladder:10.85

kidney:9.99

pituitary:11.38

thyroid/parathyroid:-

adrenal gland:10.03

pancreas:8.04

breast:9.94

salivary:7.28

CAGE

uterus:2.92

placenta:3.69

prostate:2.51

ovary:3.02

testis:1.48

heart:-

muscle:-

esophagus:-

stomach:3.42

intestine:2.10

colon:2.50

liver/hepato:4.23

lung:4.67

bladder:3.36

kidney:-

pituitary:4.00

thyroid/parathyroid:-

adrenal gland:3.81

pancreas:2.75

breast:2.96

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:5.49

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:3.60

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_013642
Gene ID	19252
Unigene ID	-
Probe set ID	1448830_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024190

Orthologous Gene

Human[2]	NM_004417
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR020417	Dual specificity phosphatase
IPR000340	Dual specificity phosphatase, catalytic domain
IPR020420	Dual specificity phosphatase, subfamily B
IPR020422	Dual specificity phosphatase, subgroup, catalytic domain
IPR014393	Dual specificity protein phosphatase (MAP kinase phosphatase)
IPR008343	MAP kinase phosphatase

GO:0007049	cell cycle
GO:0016311	dephosphorylation
GO:0001706	endoderm formation
GO:0000188	inactivation of MAPK activity
GO:0043066	negative regulation of apoptosis
GO:0043065	positive regulation of apoptosis
GO:0006470	protein amino acid dephosphorylation
GO:0042981	regulation of apoptosis

GO:0005654	nucleoplasm
GO:0005634	nucleus

GO:0016787	hydrolase activity
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity
GO:0004721	phosphoprotein phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0008330	protein tyrosine/threonine phosphatase activity

dual specificity phosphatase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function