protein tyrosine phosphatase, receptor type, F

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Synonym

LAR, AA591035, LARS, protein tyrosine phosphatase, receptor type, F, Ptprf

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:333.40 cerebellum:- brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:- retina:128.60 eye:288.70 artery/aorta:- vein:- lymphnode:32.40 peripheral blood:- spleen:26.30 thymus:49.40 bone marrow:- adipose:- bone:125.20 skin:237.50
GeneChip cerebrum:9.93 cerebellum:7.84 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.90 spine:10.07 retina:10.65 eye:11 artery/aorta:- vein:10.60 lymphnode:7.98 peripheral blood:- spleen:7.43 thymus:- bone marrow:6.61 adipose:9.10 bone:7.30 skin:12.47
CAGE cerebrum:1.88 cerebellum:- brain stem:2.63 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.83 retina:- eye:- artery/aorta:1.50 vein:- lymphnode:1.35 peripheral blood:- spleen:0.41 thymus:3.14 bone marrow:- adipose:- bone:1.30 skin:4.28
RNA-seq cerebrum:7.86 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:220.90 prostate:- ovary:114.90 testis:118.20 heart:- muscle:35.50 esophagus:- stomach:229.10 intestine:665.50 colon:176.20     liver/hepato:81.50        lung:180.80    bladder:132.40 kidney:64.50 pituitary:116.30 thyroid/parathyroid:337.40 adrenal gland:- pancreas:985.10 breast:238.30 salivary:270
GeneChip uterus:11.06 placenta:10 prostate:11.97 ovary:10.66 testis:8.40 heart:7.66 muscle:7.43 esophagus:- stomach:11.30 intestine:11.96 colon:- liver/hepato:11.17 lung:12.04 bladder:11.90 kidney:11.30 pituitary:11.06 thyroid/parathyroid:- adrenal gland:10.47 pancreas:10.30 breast:10.53 salivary:11.56
CAGE uterus:3.37 placenta:2.34 prostate:3.63 ovary:3.01 testis:1.80 heart:- muscle:- esophagus:- stomach:2.90 intestine:3.75 colon:4.19     liver/hepato:3.65    lung:3.87 bladder:3.93 kidney:- pituitary:3.43 thyroid/parathyroid:- adrenal gland:2.57 pancreas:3.16 breast:3.46 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.87 esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.94        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_011213
Gene ID 19268
Unigene ID Mm.29855
Probe set ID 1420843_at  [Mouse430_2]
Ensembl ID ENSMUSG00000033295

Orthologous Gene

Human[6]  NM_002840, NM_130440
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR000242  Protein-tyrosine phosphatase, receptor/non-receptor type

Link to Pubmed  (Pubmed ID)

1454056
1655529
2972792
7604039
7665159
7804149
7832766
8830779
8875997
8889548
9039657
9245518
9519761
9748473
9784606
10349636
10922068
11042159
11076861
11182246
11217851
11241288
11431694
11438588
12466851
12477932
12496362
12515828
12520002
12653975
12904583
14610273
14967925
15033168
15302123
15489334
15932596
16141072
16141073
16488625
16602821
17498650
17500057
17967808
18799693
18854310
19273906
19624305
19727691
19910497
20186877
21300149
21402080
21677750
21976490
22899729
23791195
23863482

Gene Ontology  (GO ID)

Biological Process

GO:0007155  cell adhesion
GO:0016311  dephosphorylation
GO:0007156  homophilic cell adhesion
GO:0031345  negative regulation of cell projection organization
GO:0008285  negative regulation of cell proliferation
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0051387  negative regulation of nerve growth factor receptor signaling pathway
GO:0007399  nervous system development
GO:0043065  positive regulation of apoptosis
GO:0050775  positive regulation of dendrite morphogenesis
GO:0043525  positive regulation of neuron apoptosis
GO:0006470  protein amino acid dephosphorylation
GO:0050803  regulation of synapse structure and activity

Cellular Component

GO:0043025  cell soma
GO:0005768  endosome
GO:0060076  excitatory synapse
GO:0030426  growth cone
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005886  plasma membrane

Molecular Function

GO:0008201  heparin binding
GO:0016787  hydrolase activity
GO:0005158  insulin receptor binding
GO:0016791  phosphatase activity
GO:0042301  phosphate binding
GO:0004721  phosphoprotein phosphatase activity
GO:0004725  protein tyrosine phosphatase activity
GO:0030971  receptor tyrosine kinase binding
GO:0005001  transmembrane receptor protein tyrosine phosphatase activity