ryanodine receptor 1, skeletal muscle

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Synonym

Ryr1, Ryr, ryanodine receptor 1, skeletal muscle, skrr, calcium release channel isoform 1, AI528790

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:- brain stem:158.90 corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:- retina:32.10 eye:38 artery/aorta:168.80 vein:- lymphnode:21.60 peripheral blood:- spleen:13.20 thymus:19.80 bone marrow:- adipose:212.70 bone:- skin:23.80
GeneChip cerebrum:6.25 cerebellum:6.99 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.08 spine:5.88 retina:3.97 eye:3.94 artery/aorta:- vein:5.79 lymphnode:6.91 peripheral blood:- spleen:6.90 thymus:- bone marrow:5.80 adipose:7.88 bone:8.37 skin:10.48
CAGE cerebrum:1.54 cerebellum:- brain stem:0.32 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.13 retina:- eye:- artery/aorta:1.62 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0.67 bone marrow:- adipose:- bone:5.08 skin:4.59
RNA-seq cerebrum:12.94 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:11.50 testis:7.40 heart:- muscle:887.70 esophagus:- stomach:- intestine:184.90 colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:16.30 salivary:-
GeneChip uterus:4.09 placenta:4.08 prostate:9.64 ovary:4.26 testis:5.49 heart:3.96 muscle:13.41 esophagus:- stomach:4.16 intestine:4.95 colon:- liver/hepato:4.19 lung:4.51 bladder:5.24 kidney:3.78 pituitary:5.21 thyroid/parathyroid:- adrenal gland:3.85 pancreas:5.48 breast:8.47 salivary:4.22
CAGE uterus:0 placenta:0.11 prostate:1.91 ovary:0.13 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:1.62 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:84.92 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.68        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_009109
Gene ID 20190
Unigene ID Mm.439745
Probe set ID 1427306_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030592

Orthologous Gene

Human[2]  NM_000540, NM_001042723
Rat[2]  NM_000540, NM_001042723

Chromosomal Region

-

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0070588  calcium ion transmembrane transport
GO:0006816  calcium ion transport
GO:0006874  cellular calcium ion homeostasis
GO:0071313  cellular response to caffeine
GO:0051480  cytosolic calcium ion homeostasis
GO:0034220  ion transmembrane transport
GO:0006811  ion transport
GO:0007275  multicellular organismal development
GO:0006936  muscle contraction
GO:0043931  ossification involved in bone maturation
GO:0003151  outflow tract morphogenesis
GO:0006937  regulation of muscle contraction
GO:0051209  release of sequestered calcium ion into cytosol
GO:0014808  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0031000  response to caffeine
GO:0001666  response to hypoxia
GO:0070296  sarcoplasmic reticulum calcium ion transport
GO:0048741  skeletal muscle fiber development
GO:0043588  skin development
GO:0055085  transmembrane transport
GO:0006810  transport

Cellular Component

GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0031234  extrinsic to internal side of plasma membrane
GO:0031674  I band
GO:0016021  integral to membrane
GO:0030314  junctional membrane complex
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0042383  sarcolemma
GO:0016529  sarcoplasmic reticulum
GO:0033017  sarcoplasmic reticulum membrane
GO:0030315  T-tubule

Molecular Function

GO:0005262  calcium channel activity
GO:0005509  calcium ion binding
GO:0005516  calmodulin binding
GO:0019899  enzyme binding
GO:0005216  ion channel activity
GO:0002020  protease binding
GO:0005515  protein binding
GO:0005219  ryanodine-sensitive calcium-release channel activity
GO:0005245  voltage-gated calcium channel activity