ryanodine receptor 2, cardiac

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Synonym

ryanodine receptor 2, cardiac, Ryr2, 9330127I20Rik

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:24.30

cerebellum:147.40

brain stem:31.80

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:32.10

eye:7.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.35

cerebellum:4.42

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:3.79

spine:4.22

retina:3.94

eye:3.96

artery/aorta:-

vein:4.04

lymphnode:3.84

peripheral blood:-

spleen:3.94

thymus:-

bone marrow:3.95

adipose:4.13

bone:3.86

skin:4.13

CAGE

cerebrum:3.71

cerebellum:-

brain stem:2.70

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.84

retina:-

eye:-

artery/aorta:1.67

vein:-

lymphnode:0.23

peripheral blood:-

spleen:0.41

thymus:0.27

bone marrow:-

adipose:-

bone:0

skin:0.97

RNA-seq

cerebrum:43.57

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:-

prostate:-

ovary:-

testis:-

heart:130.20

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:-

salivary:-

GeneChip

uterus:3.71

placenta:3.82

prostate:3.84

ovary:3.96

testis:3.69

heart:7.57

muscle:4.41

esophagus:-

stomach:4.05

intestine:3.90

colon:-

liver/hepato:4.04

lung:3.86

bladder:3.85

kidney:4

pituitary:4.01

thyroid/parathyroid:-

adrenal gland:3.82

pancreas:4.36

breast:3.93

salivary:4.11

CAGE

uterus:0.90

placenta:0.51

prostate:0

ovary:1.58

testis:0

heart:-

muscle:-

esophagus:-

stomach:0.67

intestine:0.58

colon:1.03

liver/hepato:0

lung:1.46

bladder:1.14

kidney:-

pituitary:1.31

thyroid/parathyroid:-

adrenal gland:1.75

pancreas:0

breast:0.12

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:24.05

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:13.28

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_023868
Gene ID	20191
Unigene ID	Mm.239871
Probe set ID	1421126_at [Mouse430_2]
Ensembl ID	ENSMUSG00000021313

Orthologous Gene

Human [0]
Rat[1]	NM_001191043, NM_032078

Chromosomal Region

Gene Family (Interpro ID)

IPR001870	B302 (SPRY)-like
IPR018249	EF-HAND 2
IPR003877	SPla/RYanodine receptor SPRY
IPR018355	SPla/RYanodine receptor subgroup

Gene Ontology (GO ID)

Biological Process

GO:0030509	BMP signaling pathway
GO:0070588	calcium ion transmembrane transport
GO:0006816	calcium ion transport
GO:0060402	calcium ion transport into cytosol
GO:0019722	calcium-mediated signaling
GO:0060048	cardiac muscle contraction
GO:0003300	cardiac muscle hypertrophy
GO:0006874	cellular calcium ion homeostasis
GO:0071313	cellular response to caffeine
GO:0051480	cytosolic calcium ion homeostasis
GO:0060401	cytosolic calcium ion transport
GO:0005513	detection of calcium ion
GO:0003143	embryonic heart tube morphogenesis
GO:0034220	ion transmembrane transport
GO:0006811	ion transport
GO:0003220	left ventricular cardiac muscle tissue morphogenesis
GO:0071421	manganese ion transmembrane transport
GO:0007275	multicellular organismal development
GO:0010460	positive regulation of heart rate
GO:0051284	positive regulation of sequestering of calcium ion
GO:0051481	reduction of cytosolic calcium ion concentration
GO:0055117	regulation of cardiac muscle contraction
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0002027	regulation of heart rate
GO:0051209	release of sequestered calcium ion into cytosol
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0031000	response to caffeine
GO:0051592	response to calcium ion
GO:0001666	response to hypoxia
GO:0032026	response to magnesium ion
GO:0051775	response to redox state
GO:0070296	sarcoplasmic reticulum calcium ion transport
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0031672	A band
GO:0034704	calcium channel complex
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0031234	extrinsic to internal side of plasma membrane
GO:0016021	integral to membrane
GO:0005622	intracellular
GO:0016020	membrane
GO:0043005	neuron projection
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0042383	sarcolemma
GO:0030017	sarcomere
GO:0016529	sarcoplasmic reticulum
GO:0033017	sarcoplasmic reticulum membrane
GO:0030018	Z disc

Molecular Function

GO:0005488	binding
GO:0005262	calcium channel activity
GO:0005509	calcium ion binding
GO:0048763	calcium-induced calcium release activity
GO:0015278	calcium-release channel activity
GO:0005516	calmodulin binding
GO:0019899	enzyme binding
GO:0042802	identical protein binding
GO:0005218	intracellular ligand-gated calcium channel activity
GO:0005216	ion channel activity
GO:0005515	protein binding
GO:0034236	protein kinase A catalytic subunit binding
GO:0034237	protein kinase A regulatory subunit binding
GO:0043621	protein self-association
GO:0005219	ryanodine-sensitive calcium-release channel activity
GO:0043924	suramin binding

ryanodine receptor 2, cardiac

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function