sortilin 1

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Synonym

Ntr3, neurotensin receptor 3, sortilin, mNTR3, Sortilin precursor, 2900053A11Rik, Sort1, Ntsr3, AI852375, sortilin 1, NTR3, Neurotensin receptor 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:10.44 cerebellum:9.55 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.34 spine:10.22 retina:9.61 eye:9.33 artery/aorta:- vein:8.48 lymphnode:7.62 peripheral blood:- spleen:7.78 thymus:- bone marrow:9.49 adipose:10.84 bone:9.54 skin:8.97
CAGE cerebrum:5.21 cerebellum:- brain stem:5.07 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.22 retina:- eye:- artery/aorta:5.11 vein:- lymphnode:2.72 peripheral blood:- spleen:3.55 thymus:2.88 bone marrow:- adipose:- bone:4.54 skin:4.58
RNA-seq cerebrum:23.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:9.29 placenta:6.87 prostate:10.28 ovary:8.92 testis:7.81 heart:9.02 muscle:9.74 esophagus:- stomach:9.94 intestine:10.31 colon:- liver/hepato:8.11 lung:10.52 bladder:9.39 kidney:8.23 pituitary:8.93 thyroid/parathyroid:- adrenal gland:8.91 pancreas:9.17 breast:9.25 salivary:9.97
CAGE uterus:4.31 placenta:2.44 prostate:5.24 ovary:3.79 testis:4.35 heart:- muscle:- esophagus:- stomach:4.13 intestine:4.07 colon:4.71     liver/hepato:2.53    lung:5.48 bladder:4.43 kidney:- pituitary:4.12 thyroid/parathyroid:- adrenal gland:3.53 pancreas:4.45 breast:4.46 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.82 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.83        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_019972
Gene ID 20661
Unigene ID -
Probe set ID 1423362_at  [Mouse430_2]
Ensembl ID ENSMUSG00000068747

Orthologous Gene

Human[4]  NM_001205228, NM_002959
Rat[2]  NM_031767, NM_002959

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
9452485
10064893
10085125
10349636
10390649
10594043
11042159
11076861
11217851
11322955
12466851
12477932
14610273
15078902
15236332
15236333
15372498
15489334
15747579
15782199
15992544
16141072
16141073
16602821
17220298
17934455
18258592
18287559
18687776
19219422
19407813
19521566
19732768
20080679
20133718
20405001
20571055
20686566
20805226
20816088
21040701
21092856
21102451
21261755
21267068
21402589
21565611
21677750
21730062
22262463
22302815
22466652
22558402
22579764
22723691
22751103
22781549
23084031
23091165
23236149
23283322
23283348
23313508
23704887
23904453
23966466
24355921
24506872

Gene Ontology  (GO ID)

Biological Process

GO:0030154  cell differentiation
GO:0006897  endocytosis
GO:0008333  endosome to lysosome transport
GO:0032509  endosome transport via multivesicular body sorting pathway
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0046323  glucose import
GO:0006895  Golgi to endosome transport
GO:0008625  induction of apoptosis via death domain receptors
GO:0007275  multicellular organismal development
GO:0014902  myotube differentiation
GO:0051005  negative regulation of lipoprotein lipase activity
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007218  neuropeptide signaling pathway
GO:0001503  ossification
GO:0048227  plasma membrane to endosome transport
GO:0010468  regulation of gene expression
GO:0032868  response to insulin stimulus
GO:0006810  transport
GO:0016050  vesicle organization

Cellular Component

GO:0043025  cell soma
GO:0009986  cell surface
GO:0030136  clathrin-coated vesicle
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0030425  dendrite
GO:0005769  early endosome
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0005764  lysosome
GO:0016020  membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0030140  trans-Golgi network transport vesicle

Molecular Function

GO:0019899  enzyme binding
GO:0048406  nerve growth factor binding
GO:0010465  nerve growth factor receptor activity
GO:0030379  neurotensin receptor activity, non-G-protein coupled