serine (or cysteine) peptidase inhibitor, clade A, member 1C

 jump to detail

Synonym

Serine protease inhibitor 1-3, Spi1-3, PI3, Serpina1c, Alpha-1 protease inhibitor 3, Alpha-1-antitrypsin 1-3 precursor, Dom3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:425.40 bone:- skin:-
GeneChip cerebrum:7.05 cerebellum:4.99 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.88 spine:5.71 retina:5.99 eye:6.49 artery/aorta:- vein:5.61 lymphnode:5.11 peripheral blood:- spleen:6.23 thymus:- bone marrow:4.66 adipose:5.42 bone:5.67 skin:5.74
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.14 vein:- lymphnode:0 peripheral blood:- spleen:0.16 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:44.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:27.60 prostate:- ovary:- testis:- heart:- muscle:213 esophagus:- stomach:- intestine:- colon:17.60     liver/hepato:4072.60        lung:80.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:424.40 pancreas:- breast:- salivary:54
GeneChip uterus:6.57 placenta:8.91 prostate:5.19 ovary:6.16 testis:6.23 heart:7.55 muscle:8.10 esophagus:- stomach:6.04 intestine:5.51 colon:- liver/hepato:14.70 lung:11.96 bladder:6.74 kidney:7.49 pituitary:6.75 thyroid/parathyroid:- adrenal gland:10.19 pancreas:5.39 breast:7.27 salivary:5.07
CAGE uterus:0 placenta:0.90 prostate:0 ovary:0 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:0 colon:0     liver/hepato:5.37    lung:0 bladder:0 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0.56 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.41 esophagus:- stomach:- intestine:- colon:-     liver/hepato:615.26        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_009245
Gene ID 20702
Unigene ID Mm.439694
Probe set ID 1448680_at  [Mouse430_2]
Ensembl ID ENSMUSG00000079015

Orthologous Gene

Human[22]  NM_000295, NM_001002235, NM_001002236, NM_001127700, NM_001127701, NM_001127702, NM_001127703, NM_001127704, NM_001127705, NM_001127706, NM_001127707
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1360279
1946354
6547997
8619829
9685498
9875564
11961105
12408969
12477932
12659817
15489334
15795238
16944957
19264904
21267068
24172014

Gene Ontology  (GO ID)

Biological Process

GO:0010951  negative regulation of endopeptidase activity
GO:0010466  negative regulation of peptidase activity
GO:0030162  regulation of proteolysis
GO:0034097  response to cytokine stimulus
GO:0043434  response to peptide hormone stimulus

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0004866  endopeptidase inhibitor activity
GO:0030414  peptidase inhibitor activity
GO:0002020  protease binding
GO:0004867  serine-type endopeptidase inhibitor activity