brachyury

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Synonym

me75, cou, T1, T, Tl2, low ratio, Tl3, brachyury, Low, Brachyury protein, Lr, Bra, T protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.40 cerebellum:- brain stem:158.90 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.93 cerebellum:3.94 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.77 spine:3.99 retina:4.18 eye:4.46 artery/aorta:- vein:4.05 lymphnode:3.83 peripheral blood:- spleen:3.78 thymus:- bone marrow:3.83 adipose:3.92 bone:3.93 skin:4.13
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.87 placenta:4 prostate:4.04 ovary:3.89 testis:3.95 heart:4.09 muscle:4.11 esophagus:- stomach:3.90 intestine:3.83 colon:- liver/hepato:4.13 lung:3.77 bladder:3.78 kidney:4.17 pituitary:3.82 thyroid/parathyroid:- adrenal gland:3.89 pancreas:4.63 breast:3.99 salivary:4.03
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_009309
Gene ID 20997
Unigene ID Mm.91327
Probe set ID 1419304_at  [Mouse430_2]
Ensembl ID ENSMUSG00000062327

Orthologous Gene

Human[1]  NM_003181
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR002070  Transcription factor, Brachyury
IPR001699  Transcription factor, T-box

Link to Pubmed  (Pubmed ID)

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Gene Ontology  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0009952  anterior/posterior pattern formation
GO:0030509  BMP signaling pathway
GO:0060349  bone morphogenesis
GO:0055007  cardiac muscle cell differentiation
GO:0048706  embryonic skeletal system development
GO:0003007  heart morphogenesis
GO:0007498  mesoderm development
GO:0007509  mesoderm migration
GO:0007275  multicellular organismal development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001839  neural plate morphogenesis
GO:0001843  neural tube closure
GO:0030903  notochord development
GO:0014028  notochord formation
GO:0007341  penetration of zona pellucida
GO:0008284  positive regulation of cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0003257  positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0022414  reproductive process
GO:0060395  SMAD protein signal transduction
GO:0001756  somitogenesis
GO:0006351  transcription, DNA-dependent
GO:0001570  vasculogenesis
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0000785  chromatin
GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity