transcription factor 4

Synonym

SEF2, Sef2, ITF2, SEF-2, Transcription factor 4, Tcf-4, ASP-I2, SL3-3 enhancer factor 2, Class A helix-loop-helix transcription factor ME2, ITF-2, MITF-2B, MITF-2, E2.2, Hnf-4, transcription factor 4, TFE, ME2, ITF-2b, MITF-2A, SEF2-1, 5730422P05Rik, E2-2, Itf2, Immunoglobulin transcription factor 2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:10.47

cerebellum:10.98

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.32

spine:9.57

retina:8.78

eye:9.16

artery/aorta:-

vein:9.36

lymphnode:9.53

peripheral blood:-

spleen:9.62

thymus:-

bone marrow:8.48

adipose:9.20

bone:8.92

skin:9.41

CAGE

cerebrum:5.23

cerebellum:-

brain stem:3.96

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.08

retina:-

eye:-

artery/aorta:4.13

vein:-

lymphnode:4.82

peripheral blood:-

spleen:3.34

thymus:3.27

bone marrow:-

adipose:-

bone:3.25

skin:4.16

RNA-seq

cerebrum:6.53

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:147.90

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:10.56

placenta:8.99

prostate:8.64

ovary:10.47

testis:6.78

heart:9.98

muscle:9.22

esophagus:-

stomach:8.94

intestine:8.40

colon:-

liver/hepato:7.30

lung:10.16

bladder:9.27

kidney:8.06

pituitary:9.65

thyroid/parathyroid:-

adrenal gland:10.13

pancreas:8.38

breast:9.50

salivary:9.60

CAGE

uterus:4.38

placenta:3.91

prostate:2.80

ovary:4.50

testis:2.19

heart:-

muscle:-

esophagus:-

stomach:3.39

intestine:2.86

colon:3.13

liver/hepato:2.83

lung:4.36

bladder:3.88

kidney:-

pituitary:3.97

thyroid/parathyroid:-

adrenal gland:4.20

pancreas:3.57

breast:3.88

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.74

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:2.02

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_013685
Gene ID	21413
Unigene ID	Mm.426933
Probe set ID	1416723_at [Mouse430_2]
Ensembl ID	ENSMUSG00000053477

Orthologous Gene

Human[14]	NM_001083962, NM_001243226, NM_001243227, NM_001243228, NM_001243230, NM_001243231, NM_001243232, NM_001243233, NM_001243234, NM_001243235, NM_001243236, NM_003199
Rat [0]

Chromosomal Region

18E2 [69,503,800 - 69,847,621]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0030154	cell differentiation
GO:0007275	multicellular organismal development
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007399	nervous system development
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0065004	protein-DNA complex assembly
GO:0006355	regulation of transcription, DNA-dependent
GO:0006352	transcription initiation
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0043425	bHLH transcription factor binding
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0070888	E-box binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0046983	protein dimerization activity
GO:0046982	protein heterodimerization activity
GO:0003714	transcription corepressor activity
GO:0003700	transcription factor activity

transcription factor 4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function