transglutaminase 2, C polypeptide

Synonym

transglutaminase 2, C polypeptide, tTGas, G[a]h, Protein-glutamine gamma-glutamyltransferase 2, TGC, tissue transglutaminase, tTG, TG C, TG2, Transglutaminase-2, TGase C, Tgm2, protein-glutamine gamma-glutamyltransferase, Tissue transglutaminase, TG(C)

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:72.90

cerebellum:239.50

brain stem:603.80

corpus callosum/glia:-

pineal gland:1031.20

peripheral nerve:248.40

spine:283.70

retina:-

eye:53.20

artery/aorta:2025.30

vein:-

lymphnode:140.40

peripheral blood:287.50

spleen:421.30

thymus:306.30

bone marrow:320.50

adipose:1063.60

bone:350.70

skin:277.10

GeneChip

cerebrum:7

cerebellum:7.38

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.04

spine:7.24

retina:7.62

eye:10.78

artery/aorta:-

vein:10.85

lymphnode:11.67

peripheral blood:-

spleen:10.41

thymus:-

bone marrow:9.34

adipose:10.92

bone:9.42

skin:9.86

CAGE

cerebrum:2.17

cerebellum:-

brain stem:2.42

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.50

retina:-

eye:-

artery/aorta:4.94

vein:-

lymphnode:4.37

peripheral blood:-

spleen:4.05

thymus:2.80

bone marrow:-

adipose:-

bone:3.83

skin:3.40

RNA-seq

cerebrum:3.57

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:436.20

placenta:331.40

prostate:-

ovary:195.30

testis:273.40

heart:1302.10

muscle:142

esophagus:-

stomach:261.80

intestine:702.50

colon:211.50

liver/hepato:181

lung:582.40

bladder:3772.30

kidney:427.10

pituitary:77.50

thyroid/parathyroid:112.50

adrenal gland:1273.30

pancreas:18.80

breast:228.50

salivary:108

GeneChip

uterus:13.06

placenta:12.15

prostate:10.67

ovary:11.36

testis:7.59

heart:11.60

muscle:10.42

esophagus:-

stomach:10.27

intestine:10.65

colon:-

liver/hepato:10.45

lung:12.18

bladder:12.36

kidney:11.23

pituitary:9.58

thyroid/parathyroid:-

adrenal gland:10.57

pancreas:8.56

breast:11.44

salivary:9.49

CAGE

uterus:6.76

placenta:6.20

prostate:4.31

ovary:4.86

testis:2.55

heart:-

muscle:-

esophagus:-

stomach:4.11

intestine:4.63

colon:4.83

liver/hepato:4.60

lung:5.38

bladder:5.48

kidney:-

pituitary:3.49

thyroid/parathyroid:-

adrenal gland:4.18

pancreas:3.49

breast:3.81

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:9.33

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:10.88

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_009373
Gene ID	21817
Unigene ID	Mm.330731
Probe set ID	1433428_x_at [Mouse430_2]
Ensembl ID	ENSMUSG00000037820

Orthologous Gene

Human[6]	NM_004613, NM_198951
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0043277	apoptotic cell clearance
GO:0001974	blood vessel remodeling
GO:0060445	branching involved in salivary gland morphogenesis
GO:0051482	elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0006917	induction of apoptosis
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine
GO:0008152	metabolic process
GO:0018149	peptide cross-linking
GO:0045785	positive regulation of cell adhesion
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050729	positive regulation of inflammatory response
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0051260	protein homooligomerization
GO:0060662	salivary gland cavitation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0005509	calcium ion binding
GO:0005525	GTP binding
GO:0046872	metal ion binding
GO:0019904	protein domain specific binding
GO:0003810	protein-glutamine gamma-glutamyltransferase activity
GO:0008483	transaminase activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups

transglutaminase 2, C polypeptide

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function