Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

 jump to detail

Synonym

Ctr9, KIAA0155, RNA polymerase-associated protein CTR9 homolog, Tsbp, Tsp, AA409336, Kiaa0155, SH2 domain-binding protein 1, Sh2bp1, p150TSP, mKIAA0155

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:62.50 cerebellum:202.60 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:76.40 spine:- retina:64.30 eye:121.60 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:143.80 spleen:26.30 thymus:108.70 bone marrow:- adipose:- bone:87.70 skin:47.50
GeneChip cerebrum:7.73 cerebellum:7.78 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.06 spine:7.86 retina:7.74 eye:7.51 artery/aorta:- vein:7.54 lymphnode:7.58 peripheral blood:- spleen:7.41 thymus:- bone marrow:7.82 adipose:7.68 bone:7.33 skin:7.46
CAGE cerebrum:3.77 cerebellum:- brain stem:3.83 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.94 retina:- eye:- artery/aorta:3.76 vein:- lymphnode:3.88 peripheral blood:- spleen:3.37 thymus:3.52 bone marrow:- adipose:- bone:3.44 skin:3.74
RNA-seq cerebrum:5.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:69 prostate:- ovary:11.50 testis:51.70 heart:18.60 muscle:35.50 esophagus:- stomach:- intestine:- colon:141     liver/hepato:9.10        lung:130.50    bladder:- kidney:64.50 pituitary:167.90 thyroid/parathyroid:- adrenal gland:- pancreas:75.10 breast:88.20 salivary:-
GeneChip uterus:8.37 placenta:9.41 prostate:7.83 ovary:8.06 testis:8.57 heart:6.99 muscle:7.56 esophagus:- stomach:7.33 intestine:7.60 colon:- liver/hepato:7.37 lung:7.31 bladder:8.29 kidney:7.82 pituitary:7.58 thyroid/parathyroid:- adrenal gland:7.54 pancreas:6.77 breast:7.89 salivary:8.17
CAGE uterus:4.50 placenta:4.43 prostate:3.59 ovary:4.09 testis:4.72 heart:- muscle:- esophagus:- stomach:3.13 intestine:3.41 colon:3.49     liver/hepato:3.57    lung:3.44 bladder:3.92 kidney:- pituitary:3.78 thyroid/parathyroid:- adrenal gland:3.47 pancreas:3.27 breast:3.29 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.22 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.04        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_009431
Gene ID 22083
Unigene ID Mm.255858
Probe set ID 1422680_at  [Mouse430_2]
Ensembl ID ENSMUSG00000005609

Orthologous Gene

Human[1]  NM_014633
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

8636124
8889548
10349636
10352232
10441734
10922068
11042159
11076861
11217851
11544199
12465718
12466851
12477932
15489334
15782199
16141072
16141073
17911113
19345177
20541477
21267068
21677750
23791194
24036311
24420920

Gene Ontology  (GO ID)

Biological Process

GO:0071222  cellular response to lipopolysaccharide
GO:0001711  endodermal cell fate commitment
GO:0033523  histone H2B ubiquitination
GO:0010390  histone monoubiquitination
GO:0070102  interleukin-6-mediated signaling pathway
GO:0007259  JAK-STAT cascade
GO:0045638  negative regulation of myeloid cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0051571  positive regulation of histone H3-K4 methylation
GO:0032968  positive regulation of RNA elongation from RNA polymerase II promoter
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0019827  stem cell maintenance
GO:0006351  transcription, DNA-dependent
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0016593  Cdc73/Paf1 complex
GO:0005634  nucleus

Molecular Function

GO:0005515  protein binding
GO:0042169  SH2 domain binding