titin

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Synonym

shru, 2310074I15Rik, 2310057K23Rik, D830007G01Rik, AV006427, 2310036G12Rik, connectin, 1100001C23Rik, Ttn, titin, D330041I19Rik, mdm

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.01 cerebellum:4.41 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:6.16 spine:6.96 retina:5.20 eye:5.20 artery/aorta:- vein:8.21 lymphnode:5.04 peripheral blood:- spleen:6.47 thymus:- bone marrow:5.21 adipose:8.56 bone:10.03 skin:12.01
CAGE cerebrum:0.13 cerebellum:- brain stem:0.07 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.79 retina:- eye:- artery/aorta:3.24 vein:- lymphnode:0.23 peripheral blood:- spleen:0 thymus:1.80 bone marrow:- adipose:- bone:6.65 skin:6.89
RNA-seq cerebrum:6.72 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:4.50 placenta:4.82 prostate:10.70 ovary:4.24 testis:5.01 heart:13.75 muscle:14.11 esophagus:- stomach:5.16 intestine:5.73 colon:- liver/hepato:4.78 lung:7.28 bladder:6.74 kidney:6.32 pituitary:6.52 thyroid/parathyroid:- adrenal gland:4.60 pancreas:6.46 breast:9.46 salivary:4.86
CAGE uterus:0 placenta:0.36 prostate:3.54 ovary:1.35 testis:0.45 heart:- muscle:- esophagus:- stomach:2.44 intestine:0 colon:0     liver/hepato:0    lung:3.25 bladder:1.41 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0.37 pancreas:0 breast:3.36 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:17.13 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_028004
Gene ID 22138
Unigene ID -
Probe set ID 1427446_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000051747

Orthologous Gene

Human [0]  
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR013106  Immunoglobulin V-set
IPR003596  Immunoglobulin V-set, subgroup
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

1582406
2129545
2203673
7720554
7720708
7896287
8307566
8359022
8486363
8604138
8618961
8751373
9040657
9440711
9618202
9817758
10330145
10349636
10481174
10607827
10929709
11042159
11044609
11076861
11130978
11217851
11544199
11717165
11829483
11956126
12355177
12464612
12466851
12477932
12651156
14600266
14610273
14741210
15136139
15138196
15475267
15967462
16115818
16141072
16141073
16337936
16470336
16481394
16702235
16717059
16881058
17038546
17261657
17360664
17522126
17664162
17904117
18310072
18579686
18753318
18799693
18849322
19091769
19406126
19679835
19679839
19683008
19850579
20442316
20507834
20855473
20860623
21041693
21255582
21267068
21289070
21327095
21536590
21555460
21565611
21659647
21677750
21708170
21835910
21840390
21943419
22160926
22778266
22846424
23047121
23060211
23220127
23246787
23266827
23283722
23297410
23709671
23824195
24457600
24470489

Gene Ontology  (GO ID)

Biological Process

GO:0007512  adult heart development
GO:0060048  cardiac muscle contraction
GO:0048739  cardiac muscle fiber development
GO:0003300  cardiac muscle hypertrophy
GO:0055008  cardiac muscle tissue morphogenesis
GO:0055003  cardiac myofibril assembly
GO:0043056  forward locomotion
GO:0003007  heart morphogenesis
GO:0001701  in utero embryonic development
GO:0006936  muscle contraction
GO:0030241  muscle thick filament assembly
GO:0030240  muscle thin filament assembly
GO:0016310  phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0050790  regulation of catalytic activity
GO:0045859  regulation of protein kinase activity
GO:0035023  regulation of Rho protein signal transduction
GO:0051592  response to calcium ion
GO:0045214  sarcomere organization
GO:0048769  sarcomerogenesis
GO:0055002  striated muscle cell development

Cellular Component

GO:0031672  A band
GO:0000794  condensed nuclear chromosome
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0031674  I band
GO:0031430  M band
GO:0005859  muscle myosin complex
GO:0005634  nucleus
GO:0030017  sarcomere
GO:0005865  striated muscle thin filament
GO:0030018  Z disc

Molecular Function

GO:0051015  actin filament binding
GO:0042805  actinin binding
GO:0030506  ankyrin binding
GO:0005524  ATP binding
GO:0005509  calcium ion binding
GO:0005516  calmodulin binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0046872  metal ion binding
GO:0051371  muscle alpha-actinin binding
GO:0003676  nucleic acid binding
GO:0000166  nucleotide binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0043621  protein self-association
GO:0004674  protein serine/threonine kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0005089  Rho guanyl-nucleotide exchange factor activity
GO:0005200  structural constituent of cytoskeleton
GO:0008307  structural constituent of muscle
GO:0031433  telethonin binding
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups