NADH dehydrogenase (ubiquinone) Fe-S protein 1

 jump to detail

Synonym

MGC19199, CI-75kD, Ndufs1, Complex I-75kD, 9930026A05Rik, MGC7850, 5830412M15Rik, NADH dehydrogenase (ubiquinone) Fe-S protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:156.30 cerebellum:92.10 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:114.70 spine:- retina:128.60 eye:129.20 artery/aorta:- vein:- lymphnode:97.20 peripheral blood:201.30 spleen:144.80 thymus:168 bone marrow:76.90 adipose:- bone:112.70 skin:134.60
GeneChip cerebrum:10.19 cerebellum:10.44 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.45 spine:10.31 retina:8.86 eye:8.65 artery/aorta:- vein:9.04 lymphnode:9.40 peripheral blood:- spleen:8.96 thymus:- bone marrow:9.64 adipose:10.84 bone:9.64 skin:9.66
CAGE cerebrum:4.38 cerebellum:- brain stem:4.54 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.44 retina:- eye:- artery/aorta:5.53 vein:- lymphnode:3.54 peripheral blood:- spleen:3.43 thymus:3.44 bone marrow:- adipose:- bone:3.79 skin:4.12
RNA-seq cerebrum:14.32 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:174.50 placenta:96.70 prostate:- ovary:195.30 testis:147.80 heart:446.40 muscle:106.50 esophagus:- stomach:32.70 intestine:73.90 colon:35.20     liver/hepato:72.40        lung:150.60    bladder:66.20 kidney:378.80 pituitary:142.10 thyroid/parathyroid:112.50 adrenal gland:- pancreas:112.60 breast:163.20 salivary:54
GeneChip uterus:9.32 placenta:9.03 prostate:9.56 ovary:9.83 testis:9.43 heart:12.47 muscle:11.99 esophagus:- stomach:10.44 intestine:10.35 colon:- liver/hepato:10.40 lung:9.05 bladder:9.53 kidney:11.38 pituitary:9.36 thyroid/parathyroid:- adrenal gland:10.52 pancreas:8.53 breast:10.60 salivary:9.05
CAGE uterus:3.49 placenta:3.44 prostate:3.49 ovary:3.58 testis:4.66 heart:- muscle:- esophagus:- stomach:4.31 intestine:4.33 colon:4.27     liver/hepato:4.53    lung:3.50 bladder:3.53 kidney:- pituitary:3.83 thyroid/parathyroid:- adrenal gland:3.97 pancreas:3.49 breast:3.97 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:39.38 esophagus:- stomach:- intestine:- colon:-     liver/hepato:15.69        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_001160040
Gene ID 227197
Unigene ID Mm.290791
Probe set ID 1425143_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000025968

Orthologous Gene

Human[1]  NM_001199981, NM_001199982, NM_001199983, NM_001199984, NM_005006
Rat [0]  

Chromosomal Region

1C2  [63,190,170  -  63,223,396]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11812828
12466851
12477932
12520002
12904583
14610273
14651853
14681479
14691545
15489334
15782199
16141072
16141073
16916647
16919269
17500595
17967808
18598756
18614015
18614564
18799693
21267068
21278135
21556144
23788428
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0008637  apoptotic mitochondrial changes
GO:0046034  ATP metabolic process
GO:0042773  ATP synthesis coupled electron transport
GO:0045333  cellular respiration
GO:0022900  electron transport chain
GO:0055114  oxidation reduction
GO:0051881  regulation of mitochondrial membrane potential
GO:0006810  transport

Cellular Component

GO:0016020  membrane
GO:0005743  mitochondrial inner membrane
GO:0005758  mitochondrial intermembrane space
GO:0005747  mitochondrial respiratory chain complex I
GO:0005739  mitochondrion
GO:0070469  respiratory chain

Molecular Function

GO:0051537  2 iron, 2 sulfur cluster binding
GO:0051539  4 iron, 4 sulfur cluster binding
GO:0009055  electron carrier activity
GO:0051536  iron-sulfur cluster binding
GO:0046872  metal ion binding
GO:0008137  NADH dehydrogenase (ubiquinone) activity
GO:0003954  NADH dehydrogenase activity
GO:0016491  oxidoreductase activity
GO:0016651  oxidoreductase activity, acting on NADH or NADPH