CCR4-NOT transcription complex, subunit 1

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Synonym

MGC7843, Cnot1, 6030411K04Rik, CCR4-NOT transcription complex, subunit 1, D830048B13, AA815922

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:180.60 cerebellum:18.40 brain stem:31.80 corpus callosum/glia:- pineal gland:- peripheral nerve:19.10 spine:94.60 retina:32.10 eye:341.90 artery/aorta:- vein:- lymphnode:54 peripheral blood:201.30 spleen:79 thymus:69.20 bone marrow:64.10 adipose:- bone:50.10 skin:87.10
GeneChip cerebrum:8.87 cerebellum:9.29 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.63 spine:8.32 retina:8.69 eye:8.57 artery/aorta:- vein:9.44 lymphnode:10.11 peripheral blood:- spleen:10.21 thymus:- bone marrow:10 adipose:9.32 bone:9.99 skin:9.31
CAGE cerebrum:3.48 cerebellum:- brain stem:3.04 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.09 retina:- eye:- artery/aorta:3.43 vein:- lymphnode:4.25 peripheral blood:- spleen:3.51 thymus:3.89 bone marrow:- adipose:- bone:3.41 skin:3.30
RNA-seq cerebrum:4.63 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:55.20 prostate:61.80 ovary:103.40 testis:177.40 heart:111.60 muscle:177.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:90.50        lung:60.30    bladder:66.20 kidney:72.50 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:65.70 breast:62 salivary:-
GeneChip uterus:9.71 placenta:9.70 prostate:9.77 ovary:9.80 testis:10.88 heart:9.07 muscle:9.04 esophagus:- stomach:9.72 intestine:10.11 colon:- liver/hepato:9.48 lung:9.37 bladder:9.27 kidney:9.19 pituitary:9.55 thyroid/parathyroid:- adrenal gland:8.85 pancreas:8.58 breast:9.50 salivary:8.45
CAGE uterus:3.24 placenta:3.54 prostate:3.23 ovary:3.39 testis:5.39 heart:- muscle:- esophagus:- stomach:2.90 intestine:3.48 colon:3.58     liver/hepato:3.38    lung:3.35 bladder:3.30 kidney:- pituitary:3.36 thyroid/parathyroid:- adrenal gland:3.18 pancreas:3.41 breast:3.55 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.06 esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.81        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_153164
Gene ID 234594
Unigene ID Mm.259220
Probe set ID 1434251_at  [Mouse430_2]
Ensembl ID ENSMUSG00000036550

Orthologous Gene

Human[6]  NM_016284, NM_206999
Rat[1]  NM_001134840, NM_206999

Chromosomal Region

8D1  [98,243,351  -  98,331,366]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11544199
12466851
12477932
12520002
12904583
14610273
14621295
14681479
16141072
16141073
16602821
17452450
17967808
18799693
20133598
21267068
21741365
22008794
22083510
22367759
22448252
23665500
23892456
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0031047  gene silencing by RNA
GO:0007275  multicellular organismal development
GO:0033147  negative regulation of estrogen receptor signaling pathway
GO:0048387  negative regulation of retinoic acid receptor signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0010606  positive regulation of cytoplasmic mRNA processing body assembly
GO:0060213  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0006355  regulation of transcription, DNA-dependent
GO:0006417  regulation of translation
GO:0006351  transcription, DNA-dependent
GO:0001829  trophectodermal cell differentiation

Cellular Component

GO:0030014  CCR4-NOT complex
GO:0005737  cytoplasm
GO:0000932  cytoplasmic mRNA processing body
GO:0005634  nucleus
GO:0005778  peroxisomal membrane

Molecular Function

GO:0030331  estrogen receptor binding
GO:0004535  poly(A)-specific ribonuclease activity
GO:0005515  protein binding
GO:0042974  retinoic acid receptor binding