eukaryotic translation initiation factor 2C, 1

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Synonym

Argonaute-1, eukaryotic translation initiation factor 2C, 1, Piwi/argonaute family protein meIF2C1, Ago1, eIF2C 1, Eif2c1, Eukaryotic translation initiation factor 2C 1, argonaute 1, eIF-2C 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:3.48 cerebellum:- brain stem:3.27 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.63 retina:- eye:- artery/aorta:2.67 vein:- lymphnode:2.84 peripheral blood:- spleen:2.72 thymus:2.91 bone marrow:- adipose:- bone:2.37 skin:3.36
RNA-seq cerebrum:4.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:3.13 placenta:2.03 prostate:2.94 ovary:3.17 testis:1.34 heart:- muscle:- esophagus:- stomach:2.44 intestine:2.40 colon:2.39     liver/hepato:2.98    lung:3.50 bladder:3.22 kidney:- pituitary:3.00 thyroid/parathyroid:- adrenal gland:3.00 pancreas:2.45 breast:2.99 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.24 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.54        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_153403
Gene ID 236511
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000041530

Orthologous Gene

Human[1]  NM_012199
Rat [0]  

Chromosomal Region

4D2.2  [126,112,256  -  126,145,878]

Gene Family (Interpro ID)

IPR012337  Polynucleotidyl transferase, ribonuclease H fold
IPR003165  Stem cell self-renewal protein Piwi

Link to Pubmed  (Pubmed ID)

10349636
10512203
10512872
10922068
11042159
11076861
11217851
12414724
12466851
12477932
12520002
12526743
12904583
14610273
15284456
15840001
16036130
16141072
16141073
16602821
17626790
17967808
18799693
19269368
19536157
19898466
20014101
20102707
20424607
21267068
21677750
21731673
22053081
22318144
22474261
22508726
23185045

Gene Ontology  (GO ID)

Biological Process

GO:0031047  gene silencing by RNA
GO:0035278  negative regulation of translation involved in gene silencing by miRNA
GO:0000956  nuclear-transcribed mRNA catabolic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0006417  regulation of translation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0000932  cytoplasmic mRNA processing body
GO:0035068  micro-ribonucleoprotein complex
GO:0005844  polysome
GO:0030529  ribonucleoprotein complex

Molecular Function

GO:0003676  nucleic acid binding
GO:0005515  protein binding
GO:0003723  RNA binding