proteasome (prosome, macropain) subunit, alpha type 1

 jump to detail

Synonym

Proteasome subunit alpha type 1, Proteasome component C2, Multicatalytic endopeptidase complex subunit C2, Macropain subunit C2, alpha-type, Psma1, C2, Proteasome nu chain

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:158 cerebellum:552.60 brain stem:286 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:114.70 spine:189.10 retina:192.90 eye:98.80 artery/aorta:337.60 vein:- lymphnode:54 peripheral blood:230 spleen:65.80 thymus:247 bone marrow:76.90 adipose:- bone:250.50 skin:324.60
GeneChip cerebrum:9.64 cerebellum:9.47 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.28 spine:9.33 retina:8.48 eye:8.38 artery/aorta:- vein:10.10 lymphnode:10.52 peripheral blood:- spleen:10.07 thymus:- bone marrow:10.89 adipose:10.47 bone:10.78 skin:10.05
CAGE cerebrum:4.34 cerebellum:- brain stem:4.43 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.35 retina:- eye:- artery/aorta:4.47 vein:- lymphnode:4.36 peripheral blood:- spleen:4.68 thymus:4.51 bone marrow:- adipose:- bone:4.54 skin:4.28
RNA-seq cerebrum:9.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:436.20 placenta:372.80 prostate:277.90 ovary:195.30 testis:206.90 heart:483.60 muscle:106.50 esophagus:- stomach:523.70 intestine:443.70 colon:317.20     liver/hepato:153.90        lung:421.80    bladder:661.80 kidney:266 pituitary:116.30 thyroid/parathyroid:562.40 adrenal gland:- pancreas:365.90 breast:362.40 salivary:-
GeneChip uterus:10.06 placenta:10.07 prostate:10.17 ovary:10.50 testis:8.41 heart:10.23 muscle:10.23 esophagus:- stomach:9.96 intestine:10.22 colon:- liver/hepato:10.57 lung:10.04 bladder:10.08 kidney:9.99 pituitary:10.06 thyroid/parathyroid:- adrenal gland:9.71 pancreas:8.13 breast:10.32 salivary:8.99
CAGE uterus:4.30 placenta:4.59 prostate:4.34 ovary:4.37 testis:4.30 heart:- muscle:- esophagus:- stomach:4.63 intestine:4.35 colon:4.59     liver/hepato:4.88    lung:4.33 bladder:4.41 kidney:- pituitary:4.64 thyroid/parathyroid:- adrenal gland:4.36 pancreas:3.64 breast:4.41 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:23.05 esophagus:- stomach:- intestine:- colon:-     liver/hepato:20.97        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_011965
Gene ID 26440
Unigene ID Mm.121265
Probe set ID 1415695_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030751

Orthologous Gene

Human[8]  NM_001143937, NM_002786, NM_148976
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10436176
10852819
10873386
10922068
11042159
11076861
11217851
12466851
12477932
12874245
14610273
16141072
16141073
16602821
16857966
16944949
16973439
17292860
18554416
19526544
20498273
21267068
21565611
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0002862  negative regulation of inflammatory response to antigenic stimulus
GO:0006508  proteolysis
GO:0051603  proteolysis involved in cellular protein catabolic process
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0000502  proteasome complex
GO:0005839  proteasome core complex
GO:0019773  proteasome core complex, alpha-subunit complex

Molecular Function

GO:0004175  endopeptidase activity
GO:0016787  hydrolase activity
GO:0001530  lipopolysaccharide binding
GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0004298  threonine-type endopeptidase activity