Rho guanine nucleotide exchange factor (GEF) 5

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Synonym

Rho guanine nucleotide exchange factor (GEF) 5, AW495314, 2210412D05Rik, AA717842, Arhgef5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12.20 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:22.80 artery/aorta:- vein:- lymphnode:- peripheral blood:28.80 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:110.80
GeneChip nodata
CAGE cerebrum:0.92 cerebellum:- brain stem:0.73 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.83 retina:- eye:- artery/aorta:1.78 vein:- lymphnode:1.53 peripheral blood:- spleen:0.52 thymus:0.67 bone marrow:- adipose:- bone:0.63 skin:3.81
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:82.80 prostate:92.60 ovary:- testis:22.20 heart:- muscle:35.50 esophagus:- stomach:32.70 intestine:- colon:52.90     liver/hepato:9.10        lung:50.20    bladder:132.40 kidney:24.20 pituitary:12.90 thyroid/parathyroid:- adrenal gland:- pancreas:28.10 breast:94.70 salivary:54
GeneChip nodata
CAGE uterus:3.03 placenta:3.20 prostate:3.68 ovary:2.43 testis:0 heart:- muscle:- esophagus:- stomach:3.09 intestine:3.75 colon:3.66     liver/hepato:2.13    lung:2.83 bladder:2.98 kidney:- pituitary:2.39 thyroid/parathyroid:- adrenal gland:2.06 pancreas:3.10 breast:3.06 salivary:-
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_915627
Gene ID 54324
Unigene ID Mm.320978
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Rat [0]  

Chromosomal Region

6B2.1  [43,215,643  -  43,239,319]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

8889548
10349636
10810084
11042159
11076861
11125038
11217851
11707776
12466851
12477932
16141072
16141073
16602821
19713215
21029865
21267068
21525037

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0002408  myeloid dendritic cell chemotaxis
GO:0032321  positive regulation of Rho GTPase activity
GO:0032319  regulation of Rho GTPase activity

Cellular Component

GO:0005737  cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding