ubiquitin carboxyl-terminal esterase L5

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Synonym

ubiquitin carboxyl-terminal esterase L5, Uchl5, Ubiquitin C-terminal hydrolase UCH37, Ubiquitin thioesterase L5, UCH-L5, 5830413B11Rik, Uch37, Ubiquitin carboxyl-terminal hydrolase isozyme L5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:95.50 cerebellum:36.80 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:47.30 retina:- eye:38 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:71.90 spleen:- thymus:118.60 bone marrow:115.40 adipose:- bone:37.60 skin:31.70
GeneChip cerebrum:8.93 cerebellum:8.83 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:9.60 spine:9.68 retina:8.26 eye:8.36 artery/aorta:- vein:8.62 lymphnode:9.28 peripheral blood:- spleen:8.70 thymus:- bone marrow:10.08 adipose:8.79 bone:9.85 skin:8.66
CAGE cerebrum:3.97 cerebellum:- brain stem:4.29 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.57 retina:- eye:- artery/aorta:3.54 vein:- lymphnode:4.06 peripheral blood:- spleen:4.04 thymus:4.17 bone marrow:- adipose:- bone:4.11 skin:3.85
RNA-seq cerebrum:7.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:41.40 prostate:30.90 ovary:11.50 testis:66.50 heart:37.20 muscle:35.50 esophagus:- stomach:65.50 intestine:- colon:17.60     liver/hepato:45.30        lung:60.30    bladder:- kidney:40.30 pituitary:51.70 thyroid/parathyroid:- adrenal gland:- pancreas:93.80 breast:94.70 salivary:54
GeneChip uterus:8.54 placenta:8.21 prostate:9.91 ovary:8.65 testis:9.93 heart:8.49 muscle:9.40 esophagus:- stomach:8.81 intestine:8.99 colon:- liver/hepato:8.99 lung:8.16 bladder:8.93 kidney:8.57 pituitary:8.04 thyroid/parathyroid:- adrenal gland:8.10 pancreas:9.62 breast:9.36 salivary:9.24
CAGE uterus:3.46 placenta:3.16 prostate:3.71 ovary:3.41 testis:5.01 heart:- muscle:- esophagus:- stomach:3.91 intestine:3.49 colon:3.75     liver/hepato:3.91    lung:3.33 bladder:3.44 kidney:- pituitary:3.35 thyroid/parathyroid:- adrenal gland:3.21 pancreas:4.86 breast:4.40 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:6.69 esophagus:- stomach:- intestine:- colon:-     liver/hepato:5.47        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_019562
Gene ID 56207
Unigene ID Mm.261004
Probe set ID 1419452_at  [Mouse430_2]
Ensembl ID ENSMUSG00000018189

Orthologous Gene

Human[1]  NM_001199261, NM_001199262, NM_001199263, NM_015984
Rat [0]  

Chromosomal Region

1F  [145,624,408  -  145,654,596]

Gene Family (Interpro ID)

IPR001578  Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1
IPR017390  Ubiquitinyl hydrolase, UCH37 type

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11389549
12466851
12477932
14610273
15489334
15489855
16027725
16141072
16141073
18799693
21048919
21267068
23341450
23500140
23892456

Gene Ontology  (GO ID)

Biological Process

GO:0006310  DNA recombination
GO:0006281  DNA repair
GO:0048853  forebrain morphogenesis
GO:0021670  lateral ventricle development
GO:0030901  midbrain development
GO:0010951  negative regulation of endopeptidase activity
GO:0016579  protein deubiquitination
GO:0006508  proteolysis
GO:0006355  regulation of transcription, DNA-dependent
GO:0006974  response to DNA damage stimulus
GO:0006351  transcription, DNA-dependent
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0031011  Ino80 complex
GO:0005622  intracellular
GO:0005634  nucleus
GO:0000502  proteasome complex

Molecular Function

GO:0008234  cysteine-type peptidase activity
GO:0004866  endopeptidase inhibitor activity
GO:0016787  hydrolase activity
GO:0008242  omega peptidase activity
GO:0008233  peptidase activity
GO:0070628  proteasome binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity