prostaglandin E synthase 3 (cytosolic)

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Synonym

5730442A20Rik, Hsp90 co-chaperone, Ptges3, Telomerase-binding protein p23, Tebp, Progesterone receptor complex p23, Cytosolic prostaglandin E2 synthase, prostaglandin E synthase 3 (cytosolic), cPGES, Prostaglandin E synthase 3, Sid3177, sid3177, Sid 3177, Ptges

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:50.40 cerebellum:- brain stem:63.60 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:95.50 spine:189.10 retina:128.60 eye:15.20 artery/aorta:168.80 vein:- lymphnode:- peripheral blood:- spleen:26.30 thymus:49.40 bone marrow:128.20 adipose:- bone:87.70 skin:63.30
GeneChip cerebrum:11.25 cerebellum:10.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.82 spine:11.23 retina:9.91 eye:10.37 artery/aorta:- vein:11.36 lymphnode:11 peripheral blood:- spleen:11.14 thymus:- bone marrow:11.25 adipose:10.93 bone:11.18 skin:11.26
CAGE nodata
RNA-seq cerebrum:10.54 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:41.40 prostate:30.90 ovary:11.50 testis:59.10 heart:74.40 muscle:142 esophagus:- stomach:32.70 intestine:- colon:52.90     liver/hepato:27.20        lung:20.10    bladder:66.20 kidney:40.30 pituitary:38.80 thyroid/parathyroid:112.50 adrenal gland:- pancreas:178.30 breast:52.20 salivary:108
GeneChip uterus:11.28 placenta:11.17 prostate:11.39 ovary:11.49 testis:11.57 heart:10.63 muscle:11.11 esophagus:- stomach:11.09 intestine:11.17 colon:- liver/hepato:11.23 lung:11.69 bladder:11.40 kidney:10.92 pituitary:11.62 thyroid/parathyroid:- adrenal gland:11.60 pancreas:10.30 breast:11.14 salivary:11.09
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:11.77 esophagus:- stomach:- intestine:- colon:-     liver/hepato:29.66        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_019766
Gene ID 56351
Unigene ID Mm.305816
Probe set ID 1460221_at  [Mouse430_2]
Ensembl ID ENSMUSG00000071072

Orthologous Gene

Human[1]  NM_006601
Rat[1]  NM_006601

Chromosomal Region

-

Gene Family (Interpro ID)

IPR007052  CS domain
IPR008978  HSP20-like chaperone

Link to Pubmed  (Pubmed ID)

8772199
10349636
10512203
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14563409
14610273
15118109
15345747
15378723
15489334
15840001
16141072
16141073
17000766
17110338
17114649
17283187
17438133
17719010
17967808
18362168
18723680
18799693
21267068
21323770
21334450
21691801
21853119
22123826
22277657
22759865
23022381
23022695
23649778
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0070389  chaperone cofactor-dependent protein refolding
GO:0042921  glucocorticoid receptor signaling pathway
GO:0005978  glycogen biosynthetic process
GO:0060430  lung saccule development
GO:0060548  negative regulation of cell death
GO:0010628  positive regulation of gene expression
GO:0001516  prostaglandin biosynthetic process
GO:0006693  prostaglandin metabolic process
GO:0019233  sensory perception of pain
GO:0043588  skin development

Cellular Component

GO:0005884  actin filament
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0043234  protein complex
GO:0005697  telomerase holoenzyme complex

Molecular Function

GO:0019899  enzyme binding
GO:0051879  Hsp90 protein binding
GO:0002039  p53 binding
GO:0050220  prostaglandin-E synthase activity
GO:0003720  telomerase activity
GO:0051082  unfolded protein binding