STIP1 homology and U-Box containing protein 1

Synonym

2210017D18Rik, CHIP, STIP1 homology and U-box-containing protein 1, STIP1 homology and U-Box containing protein 1, Chip, AW046544, Stub1, 2310040B03Rik, 0610033N24Rik, Carboxy terminus of Hsp70-interacting protein, E3 ubiquitin protein ligase CHIP, STIP1 homology and U box-containing protein 1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:159.80

cerebellum:36.80

brain stem:127.10

corpus callosum/glia:-

pineal gland:-

peripheral nerve:114.70

spine:94.60

retina:321.40

eye:83.60

artery/aorta:84.40

vein:-

lymphnode:32.40

peripheral blood:71.90

spleen:65.80

thymus:39.50

bone marrow:38.50

adipose:-

bone:162.80

skin:87.10

GeneChip

cerebrum:10.89

cerebellum:10.84

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:10.96

spine:10.88

retina:8.95

eye:9.18

artery/aorta:-

vein:10.41

lymphnode:10.47

peripheral blood:-

spleen:10.33

thymus:-

bone marrow:10.24

adipose:10.48

bone:9.71

skin:10.21

CAGE

cerebrum:4.57

cerebellum:-

brain stem:4.88

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.78

retina:-

eye:-

artery/aorta:3.66

vein:-

lymphnode:3.48

peripheral blood:-

spleen:3.92

thymus:3.85

bone marrow:-

adipose:-

bone:4.13

skin:4.18

RNA-seq

cerebrum:7.52

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:130.90

placenta:207.10

prostate:61.80

ovary:23

testis:51.70

heart:148.80

muscle:142

esophagus:-

stomach:65.50

intestine:184.90

colon:123.40

liver/hepato:63.40

lung:210.90

bladder:-

kidney:64.50

pituitary:206.70

thyroid/parathyroid:449.90

adrenal gland:-

pancreas:131.40

breast:97.90

salivary:108

GeneChip

uterus:10.76

placenta:10.66

prostate:10.81

ovary:10.66

testis:9.73

heart:10.56

muscle:10.92

esophagus:-

stomach:10.44

intestine:10.40

colon:-

liver/hepato:9.91

lung:10.25

bladder:10.31

kidney:10.05

pituitary:11.42

thyroid/parathyroid:-

adrenal gland:11.39

pancreas:10.46

breast:10.22

salivary:10.75

CAGE

uterus:4.18

placenta:4.51

prostate:4.50

ovary:4.12

testis:4.61

heart:-

muscle:-

esophagus:-

stomach:4.23

intestine:4.31

colon:4.23

liver/hepato:4.30

lung:4.19

bladder:4.32

kidney:-

pituitary:4.65

thyroid/parathyroid:-

adrenal gland:4.66

pancreas:4.51

breast:3.99

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:10.53

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:11.90

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_019719
Gene ID	56424
Unigene ID	Mm.277599
Probe set ID	1416580_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000039615

Orthologous Gene

Human[1]	NM_005861
Rat[1]	NM_001025625

Chromosomal Region

Gene Family (Interpro ID)

IPR019734	Tetratricopeptide repeat
IPR003613	U box domain
IPR013083	Zinc finger, RING/FYVE/PHD-type

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0071218	cellular response to misfolded protein
GO:0006281	DNA repair
GO:0006515	misfolded or incompletely synthesized protein catabolic process
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031398	positive regulation of protein ubiquitination
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
GO:0051865	protein autoubiquitination
GO:0006457	protein folding
GO:0070534	protein K63-linked ubiquitination
GO:0051604	protein maturation
GO:0000209	protein polyubiquitination
GO:0016567	protein ubiquitination
GO:0031943	regulation of glucocorticoid metabolic process
GO:0006974	response to DNA damage stimulus
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0030579	ubiquitin-dependent SMAD protein catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0042405	nuclear inclusion body
GO:0031371	ubiquitin conjugating enzyme complex
GO:0000151	ubiquitin ligase complex

Molecular Function

GO:0019899	enzyme binding
GO:0031072	heat shock protein binding
GO:0030544	Hsp70 protein binding
GO:0051879	Hsp90 protein binding
GO:0019900	kinase binding
GO:0016874	ligase activity
GO:0051787	misfolded protein binding
GO:0005515	protein binding
GO:0030674	protein binding, bridging
GO:0042803	protein homodimerization activity
GO:0046332	SMAD binding
GO:0030911	TPR domain binding
GO:0031625	ubiquitin protein ligase binding
GO:0004842	ubiquitin-protein ligase activity
GO:0034450	ubiquitin-ubiquitin ligase activity

STIP1 homology and U-Box containing protein 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function