aldo-keto reductase family 1, member A4 (aldehyde reductase)

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Synonym

2610201A18Rik, Alcohol dehydrogenase [NADP+], Akr1a4, Akr1a1, Aldo-keto reductase family 1 member A1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:246.60 cerebellum:165.80 brain stem:- corpus callosum/glia:- pineal gland:257.80 peripheral nerve:229.30 spine:141.90 retina:482.20 eye:220.40 artery/aorta:- vein:- lymphnode:54 peripheral blood:143.80 spleen:65.80 thymus:118.60 bone marrow:743.60 adipose:212.70 bone:889.20 skin:324.60
GeneChip cerebrum:12.86 cerebellum:12.61 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:13.80 spine:12.61 retina:12.64 eye:12.94 artery/aorta:- vein:13.17 lymphnode:12.90 peripheral blood:- spleen:12.42 thymus:- bone marrow:12.65 adipose:13.21 bone:12.81 skin:12.70
CAGE cerebrum:4.86 cerebellum:- brain stem:5.26 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.07 retina:- eye:- artery/aorta:4.99 vein:- lymphnode:4.37 peripheral blood:- spleen:4.67 thymus:4.83 bone marrow:- adipose:- bone:4.81 skin:4.73
RNA-seq cerebrum:90.83 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:392.60 placenta:386.60 prostate:339.70 ovary:367.70 testis:170 heart:465 muscle:461.60 esophagus:- stomach:327.30 intestine:443.70 colon:563.90     liver/hepato:588.30        lung:974.10    bladder:463.30 kidney:2683.80 pituitary:284.20 thyroid/parathyroid:674.80 adrenal gland:- pancreas:150.10 breast:447.30 salivary:324
GeneChip uterus:13.12 placenta:12.83 prostate:13.25 ovary:13.27 testis:10.77 heart:12.38 muscle:12.34 esophagus:- stomach:13.16 intestine:13.19 colon:- liver/hepato:13.40 lung:13.33 bladder:13.03 kidney:14.36 pituitary:13.16 thyroid/parathyroid:- adrenal gland:13.82 pancreas:12.33 breast:12.74 salivary:13.12
CAGE uterus:5.26 placenta:5.33 prostate:5.64 ovary:5.22 testis:4.68 heart:- muscle:- esophagus:- stomach:5.81 intestine:5.82 colon:6.06     liver/hepato:5.94    lung:5.32 bladder:5.18 kidney:- pituitary:5.29 thyroid/parathyroid:- adrenal gland:5.71 pancreas:5.03 breast:5.04 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:42.93 esophagus:- stomach:- intestine:- colon:-     liver/hepato:119.38        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_021473
Gene ID 58810
Unigene ID Mm.30085
Probe set ID 1430123_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028692

Orthologous Gene

Human[2]  NM_001202413, NM_001202414, NM_006066, NM_153326
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001395  Aldo/keto reductase
IPR020471  Aldo/keto reductase subgroup

Link to Pubmed  (Pubmed ID)

8889548
10349636
10842086
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14610273
14667815
14681479
15489334
15769935
15782199
16141072
16141073
18799693
20097305
20410296
21677750
22820017
23143230

Gene Ontology  (GO ID)

Biological Process

GO:0046185  aldehyde catabolic process
GO:0042840  D-glucuronate catabolic process
GO:0019853  L-ascorbic acid biosynthetic process
GO:0055114  oxidation reduction

Cellular Component

GO:0016324  apical plasma membrane
GO:0005829  cytosol

Molecular Function

GO:0008106  alcohol dehydrogenase (NADP+) activity
GO:0004032  aldehyde reductase activity
GO:0047939  L-glucuronate reductase activity
GO:0016491  oxidoreductase activity