coactivator-associated arginine methyltransferase 1

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Synonym

Carm1, Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 4, MGC46828, Prmt4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26 cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:15.20 artery/aorta:- vein:- lymphnode:- peripheral blood:14.40 spleen:- thymus:9.90 bone marrow:12.80 adipose:- bone:62.60 skin:39.60
GeneChip cerebrum:8.73 cerebellum:7.82 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.54 spine:8.54 retina:8.15 eye:8.22 artery/aorta:- vein:8.77 lymphnode:8.06 peripheral blood:- spleen:8.30 thymus:- bone marrow:9.01 adipose:8.18 bone:8.43 skin:8.09
CAGE cerebrum:2.92 cerebellum:- brain stem:3.02 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.15 retina:- eye:- artery/aorta:3.10 vein:- lymphnode:2.98 peripheral blood:- spleen:2.89 thymus:2.11 bone marrow:- adipose:- bone:3.41 skin:3.01
RNA-seq cerebrum:9.49 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:69 prostate:30.90 ovary:- testis:- heart:- muscle:35.50 esophagus:- stomach:- intestine:- colon:70.50     liver/hepato:63.40        lung:60.30    bladder:- kidney:24.20 pituitary:- thyroid/parathyroid:112.50 adrenal gland:- pancreas:- breast:42.40 salivary:162
GeneChip uterus:9.13 placenta:8.41 prostate:8.44 ovary:8.90 testis:9.14 heart:9.36 muscle:10.08 esophagus:- stomach:8.31 intestine:8.33 colon:- liver/hepato:8.48 lung:8.24 bladder:8.39 kidney:8.07 pituitary:8.78 thyroid/parathyroid:- adrenal gland:8.15 pancreas:8.25 breast:8.60 salivary:8.61
CAGE uterus:3.37 placenta:3.21 prostate:2.54 ovary:3.21 testis:4.45 heart:- muscle:- esophagus:- stomach:2.66 intestine:2.67 colon:2.82     liver/hepato:2.90    lung:2.71 bladder:2.93 kidney:- pituitary:3.28 thyroid/parathyroid:- adrenal gland:2.91 pancreas:2.45 breast:2.67 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:7.92 esophagus:- stomach:- intestine:- colon:-     liver/hepato:3.50        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_153141
Gene ID 59035
Unigene ID Mm.178115
Probe set ID 1419743_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000032185

Orthologous Gene

Human[1]  NM_199141
Rat [0]  

Chromosomal Region

9A3  [21,351,338  -  21,393,931]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10381882
10922068
11042159
11076861
11217851
11341840
11701890
11713257
11747826
11751582
11850402
11983685
11997499
12237300
12351636
12466851
12477932
12498683
12520002
12756295
12904583
14610273
14690606
14966289
15096520
15186775
15339660
15489334
15616592
15782199
16033648
16141072
16141073
16508003
16602821
16618939
16690984
17043108
17124247
17215844
17218272
17640894
17882261
17882262
17967808
18023262
18188184
18280497
18511550
18799693
18840611
19188441
19544422
19598128
19725955
19769987
19843527
19897492
20059953
20111005
20530543
21126607
21138967
21245169
21454787
21930775
22046437
22251447
22428544
22723830
22863532
23136128
23248263
24183668
24434208
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0060350  endochondral bone morphogenesis
GO:0030520  estrogen receptor signaling pathway
GO:0034969  histone arginine methylation
GO:0034971  histone H3-R17 methylation
GO:0034970  histone H3-R2 methylation
GO:0016571  histone methylation
GO:0032259  methylation
GO:0032091  negative regulation of protein binding
GO:0009405  pathogenesis
GO:0019919  peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0035246  peptidyl-arginine N-methylation
GO:0008284  positive regulation of cell proliferation
GO:0045600  positive regulation of fat cell differentiation
GO:0006479  protein amino acid methylation
GO:0033146  regulation of estrogen receptor signaling pathway
GO:0003420  regulation of growth plate cartilage chondrocyte proliferation
GO:0006355  regulation of transcription, DNA-dependent
GO:0051591  response to cAMP
GO:0030518  steroid hormone receptor signaling pathway
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0044212  DNA regulatory region binding
GO:0070577  histone acetyl-lysine binding
GO:0042054  histone methyltransferase activity
GO:0008469  histone-arginine N-methyltransferase activity
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0008168  methyltransferase activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0008276  protein methyltransferase activity
GO:0016274  protein-arginine N-methyltransferase activity
GO:0035242  protein-arginine omega-N asymmetric methyltransferase activity
GO:0003713  transcription coactivator activity
GO:0016740  transferase activity