aspartate-beta-hydroxylase

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Synonym

calsequestrin-binding protein, BAH, 2310005F16Rik, Junctin, 3110001L23Rik, aspartate-beta-hydroxylase, jumbug, AW561901, AI848629, AW261690, Asph, aspartyl beta-hydroxylase, cI-37, junctate

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:18.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.67 cerebellum:7.43 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.92 spine:5.80 retina:5.87 eye:5.72 artery/aorta:- vein:5.53 lymphnode:4.89 peripheral blood:- spleen:5.03 thymus:- bone marrow:5.33 adipose:7.11 bone:6.87 skin:8.50
CAGE cerebrum:5.29 cerebellum:- brain stem:4.49 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.66 retina:- eye:- artery/aorta:5.04 vein:- lymphnode:3.74 peripheral blood:- spleen:3.76 thymus:2.61 bone marrow:- adipose:- bone:4.59 skin:4.90
RNA-seq cerebrum:13.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.93 placenta:5 prostate:6.33 ovary:4.84 testis:4.99 heart:10.42 muscle:11.77 esophagus:- stomach:5.28 intestine:5.22 colon:- liver/hepato:5.24 lung:5.04 bladder:5.20 kidney:5.11 pituitary:5.19 thyroid/parathyroid:- adrenal gland:4.93 pancreas:6.36 breast:8.26 salivary:5.76
CAGE uterus:4.16 placenta:3.73 prostate:5.08 ovary:4.60 testis:2.19 heart:- muscle:- esophagus:- stomach:4.57 intestine:3.97 colon:3.98     liver/hepato:4.25    lung:4.17 bladder:4.72 kidney:- pituitary:4.84 thyroid/parathyroid:- adrenal gland:4.41 pancreas:4.32 breast:3.98 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:48.25 esophagus:- stomach:- intestine:- colon:-     liver/hepato:4.53        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_133723
Gene ID 65973
Unigene ID Mm.412008
Probe set ID 1425275_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028207

Orthologous Gene

Human[51]  NM_001164750, NM_001164751, NM_001164752, NM_001164753, NM_001164754, NM_001164755, NM_001164756, NM_004318, NM_020164, NM_032466, NM_032467, NM_032468
Rat[51]  NM_001164750, NM_001164751, NM_001164752, NM_001164753, NM_001164754, NM_001164755, NM_001164756, NM_004318, NM_020164, NM_032466, NM_032467, NM_032468

Chromosomal Region

-

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

8530521
8889548
10349636
10725249
10922068
10956665
11004510
11042159
11076861
11217851
11356033
11735129
11773073
12154005
12466851
12477932
12520002
12904583
15747579
15777620
16104381
16141072
16141073
16153633
16289269
16602821
17224479
17500595
17516551
17706594
17890426
18353357
18620751
19075228
19286959
19386262
19663697
19896466
21267068
21406540
22005675
22025663
22123818
22411973
22768324
23341629

Gene Ontology  (GO ID)

Biological Process

GO:0032237  activation of store-operated calcium channel activity
GO:0070588  calcium ion transmembrane transport
GO:0071277  cellular response to calcium ion
GO:0060325  face morphogenesis
GO:0035108  limb morphogenesis
GO:0008285  negative regulation of cell proliferation
GO:0055114  oxidation reduction
GO:0060021  palate development
GO:0007389  pattern specification process
GO:0018193  peptidyl-amino acid modification
GO:0042264  peptidyl-aspartic acid hydroxylation
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0045862  positive regulation of proteolysis
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0031585  regulation of inositol-1,4,5-triphosphate receptor activity
GO:0031647  regulation of protein stability
GO:0033198  response to ATP

Cellular Component

GO:0032541  cortical endoplasmic reticulum
GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0030176  integral to endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0016491  oxidoreductase activity
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0004597  peptide-aspartate beta-dioxygenase activity
GO:0005515  protein binding