ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)

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Synonym

E2(17)KB 3, Ubiquitin-conjugating enzyme E2 D3, 9430029A22Rik, 1100001F19Rik, AA414951, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase D3, Ube2d3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:15.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:257.80 peripheral nerve:- spine:- retina:- eye:22.80 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:14.40 spleen:26.30 thymus:- bone marrow:- adipose:- bone:- skin:55.40
GeneChip cerebrum:10.97 cerebellum:11.06 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:11.28 spine:10.58 retina:10.65 eye:10.79 artery/aorta:- vein:10.77 lymphnode:11.21 peripheral blood:- spleen:10.95 thymus:- bone marrow:10.89 adipose:10.69 bone:10.87 skin:10.90
CAGE cerebrum:4.53 cerebellum:- brain stem:4.61 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.75 retina:- eye:- artery/aorta:5.31 vein:- lymphnode:5.67 peripheral blood:- spleen:4.66 thymus:4.91 bone marrow:- adipose:- bone:4.90 skin:5.14
RNA-seq cerebrum:15.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:27.60 prostate:- ovary:34.50 testis:7.40 heart:18.60 muscle:- esophagus:- stomach:32.70 intestine:- colon:35.20     liver/hepato:9.10        lung:10    bladder:- kidney:8.10 pituitary:38.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:13.10 salivary:-
GeneChip uterus:10.67 placenta:10.58 prostate:10.79 ovary:11.01 testis:8.64 heart:11.01 muscle:11.48 esophagus:- stomach:10.73 intestine:10.88 colon:- liver/hepato:10.87 lung:11.01 bladder:10.98 kidney:11.02 pituitary:11.11 thyroid/parathyroid:- adrenal gland:10.73 pancreas:10.08 breast:10.95 salivary:10.90
CAGE uterus:4.82 placenta:5.38 prostate:4.79 ovary:4.56 testis:6.46 heart:- muscle:- esophagus:- stomach:5.31 intestine:5.32 colon:5.10     liver/hepato:5.51    lung:4.84 bladder:4.78 kidney:- pituitary:4.46 thyroid/parathyroid:- adrenal gland:4.69 pancreas:4.61 breast:4.86 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:31.68 esophagus:- stomach:- intestine:- colon:-     liver/hepato:30.56        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_025356
Gene ID 66105
Unigene ID Mm.391601
Probe set ID 1450858_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000078578

Orthologous Gene

Human[27]  NM_003340, NM_181886, NM_181887, NM_181888, NM_181889, NM_181890, NM_181891, NM_181892, NM_181893
Rat[2]  NM_001037292, NM_031237, NM_181887, NM_181888, NM_181889, NM_181890, NM_181891, NM_181892, NM_181893

Chromosomal Region

-

Gene Family (Interpro ID)

IPR000608  Ubiquitin-conjugating enzyme, E2
IPR016135  Ubiquitin-conjugating enzyme/RWD-like

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14610273
15489334
15601779
15782199
16141072
16141073
16325481
16602821
18515077
18799693
20185725
21267068
21765415
23509263
24034696

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0006281  DNA repair
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0070979  protein K11-linked ubiquitination
GO:0070936  protein K48-linked ubiquitination
GO:0006513  protein monoubiquitination
GO:0000209  protein polyubiquitination
GO:0016567  protein ubiquitination
GO:0006974  response to DNA damage stimulus
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005575  cellular_component
GO:0005768  endosome
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0016881  acid-amino acid ligase activity
GO:0005524  ATP binding
GO:0016874  ligase activity
GO:0000166  nucleotide binding
GO:0004842  ubiquitin-protein ligase activity