fission 1 (mitochondrial outer membrane) homolog (yeast)

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Synonym

Tetratricopeptide repeat protein 11, 2010003O14Rik, Fis1 homolog, TPR repeat protein 11, Ttc11, Fis1, Mitochondrial fission 1 protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:29.50 cerebellum:36.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:96.40 eye:60.80 artery/aorta:84.40 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:15.80
GeneChip cerebrum:9.98 cerebellum:9.65 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.26 spine:10.27 retina:8.82 eye:8.93 artery/aorta:- vein:9.38 lymphnode:10.20 peripheral blood:- spleen:9.91 thymus:- bone marrow:10.67 adipose:9.65 bone:10.11 skin:9.29
CAGE cerebrum:4.78 cerebellum:- brain stem:5.22 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:5.10 retina:- eye:- artery/aorta:4.10 vein:- lymphnode:4.24 peripheral blood:- spleen:4.93 thymus:4.48 bone marrow:- adipose:- bone:5.00 skin:4.24
RNA-seq cerebrum:61.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:20.10    bladder:- kidney:24.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.80 salivary:-
GeneChip uterus:9.84 placenta:9.17 prostate:9.94 ovary:9.72 testis:8.81 heart:9.07 muscle:9.97 esophagus:- stomach:9.37 intestine:9.76 colon:- liver/hepato:9.43 lung:9.96 bladder:9.13 kidney:9.96 pituitary:9.65 thyroid/parathyroid:- adrenal gland:9.58 pancreas:9.01 breast:9.48 salivary:9.45
CAGE uterus:4.37 placenta:4.30 prostate:4.45 ovary:4.26 testis:4.87 heart:- muscle:- esophagus:- stomach:4.72 intestine:4.73 colon:4.83     liver/hepato:4.84    lung:4.77 bladder:4.37 kidney:- pituitary:4.50 thyroid/parathyroid:- adrenal gland:4.43 pancreas:4.08 breast:4.09 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:33.96 esophagus:- stomach:- intestine:- colon:-     liver/hepato:19.85        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_025562
Gene ID 66437
Unigene ID Mm.258491
Probe set ID 1416764_at  [Mouse430_2]
Ensembl ID ENSMUSG00000019054

Orthologous Gene

Human[1]  NM_016068
Rat[2]  NM_001105919

Chromosomal Region

5G2  [137,429,145  -  137,442,104]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
12466851
12477932
12520002
14561759
14610273
14651853
14996942
15489334
16141072
16141073
17035996
17408615
18614015
18799693
19578372
21149567
21267068
21642619
22510686
22639965
23283981
23921378

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0051561  elevation of mitochondrial calcium ion concentration
GO:0000266  mitochondrial fission
GO:0043653  mitochondrial fragmentation during apoptosis
GO:0000422  mitochondrion degradation
GO:0070584  mitochondrion morphogenesis
GO:0016559  peroxisome fission
GO:0043280  positive regulation of caspase activity
GO:0051260  protein homooligomerization
GO:0006626  protein targeting to mitochondrion
GO:0032471  reduction of endoplasmic reticulum calcium ion concentration
GO:0010821  regulation of mitochondrion organization
GO:0001836  release of cytochrome c from mitochondria

Cellular Component

GO:0016021  integral to membrane
GO:0031307  integral to mitochondrial outer membrane
GO:0005779  integral to peroxisomal membrane
GO:0016020  membrane
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion
GO:0005777  peroxisome
GO:0043234  protein complex

Molecular Function

GO:0005102  receptor binding