ribosomal protein S6 kinase, polypeptide 1

Synonym

Rps6kb1, p70s6k, P70S6K, p70-S6K, 4732464A07Rik, p70 S6 kinase alpha, Ribosomal protein S6 kinase beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, AI314060, 2610318I15Rik, p70(S6K)-alpha, AI256796, AA959758, ribosomal protein S6 kinase, polypeptide 1, p70/85s6k, S6K

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:39.50

bone marrow:-

adipose:-

bone:-

skin:7.90

GeneChip

cerebrum:8.48

cerebellum:8.70

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:8.76

spine:8.37

retina:8.64

eye:8.56

artery/aorta:-

vein:9.01

lymphnode:8.97

peripheral blood:-

spleen:8.88

thymus:-

bone marrow:9.06

adipose:9.15

bone:8.87

skin:8.97

CAGE

cerebrum:4.11

cerebellum:-

brain stem:3.95

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.96

retina:-

eye:-

artery/aorta:4.60

vein:-

lymphnode:4.75

peripheral blood:-

spleen:4.12

thymus:4.85

bone marrow:-

adipose:-

bone:4.34

skin:4.54

RNA-seq

cerebrum:2.14

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:30.90

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:3.30

salivary:-

GeneChip

uterus:8.23

placenta:8.57

prostate:8.94

ovary:8.82

testis:7.38

heart:8.94

muscle:9.22

esophagus:-

stomach:8.31

intestine:8.53

colon:-

liver/hepato:8.80

lung:8.52

bladder:8.92

kidney:8.51

pituitary:8.39

thyroid/parathyroid:-

adrenal gland:9.60

pancreas:9.27

breast:8.95

salivary:9.78

CAGE

uterus:4.09

placenta:4.00

prostate:4.33

ovary:4.00

testis:3.55

heart:-

muscle:-

esophagus:-

stomach:4.11

intestine:3.92

colon:4.07

liver/hepato:4.20

lung:4.09

bladder:3.92

kidney:-

pituitary:3.86

thyroid/parathyroid:-

adrenal gland:3.98

pancreas:5.42

breast:4.47

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:4.97

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:7.86

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001114334
Gene ID	72508
Unigene ID	Mm.446624
Probe set ID	1460705_at [Mouse430_2]
Ensembl ID	ENSMUSG00000020516

Orthologous Gene

Human[2]	NM_003161
Rat [0]

Chromosomal Region

11C [86,312,373 - 86,358,307]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0007049	cell cycle
GO:0071363	cellular response to growth factor stimulus
GO:0000082	G1/S transition of mitotic cell cycle
GO:0007281	germ cell development
GO:0043066	negative regulation of apoptosis
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0016310	phosphorylation
GO:0045931	positive regulation of mitotic cell cycle
GO:0048633	positive regulation of skeletal muscle tissue growth
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045727	positive regulation of translation
GO:0045948	positive regulation of translational initiation
GO:0006468	protein amino acid phosphorylation
GO:0043491	protein kinase B signaling cascade
GO:0046324	regulation of glucose import
GO:0006417	regulation of translation
GO:0032868	response to insulin stimulus
GO:0034612	response to tumor necrosis factor
GO:0007165	signal transduction
GO:0031929	TOR signaling pathway

Cellular Component

GO:0030054	cell junction
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0005741	mitochondrial outer membrane
GO:0005739	mitochondrion
GO:0043005	neuron projection
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0045202	synapse

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0042277	peptide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004711	ribosomal protein S6 kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

ribosomal protein S6 kinase, polypeptide 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function