SIX homeobox 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:235.40
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:113.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:355.30 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001080688
Gene ID 114634
Unigene ID Rn.23396
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

6q24  [95,470,153  -  95,475,389]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

12834866
15141091
17637804
18330911
19389353
24528972

Gene Ontology  (GO ID)

Biological Process

GO:0048856  anatomical structure development
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0090103  cochlea morphogenesis
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0048704  embryonic skeletal system morphogenesis
GO:0030855  epithelial cell differentiation
GO:0021610  facial nerve morphogenesis
GO:0048699  generation of neurons
GO:0001759  induction of an organ
GO:0048839  inner ear development
GO:0042472  inner ear morphogenesis
GO:0001822  kidney development
GO:0042474  middle ear morphogenesis
GO:0051451  myoblast migration
GO:0090191  negative regulation of branching involved in ureteric bud morphogenesis
GO:0043524  negative regulation of neuron apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048665  neuron fate specification
GO:0003151  outflow tract morphogenesis
GO:0007389  pattern specification process
GO:0060037  pharyngeal system development
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0034504  protein localization in nucleus
GO:0010468  regulation of gene expression
GO:0045664  regulation of neuron differentiation
GO:0032880  regulation of protein localization
GO:0008582  regulation of synaptic growth at neuromuscular junction
GO:0006355  regulation of transcription, DNA-dependent
GO:0007605  sensory perception of sound
GO:0007519  skeletal muscle tissue development
GO:0048705  skeletal system morphogenesis
GO:0048538  thymus development
GO:0030878  thyroid gland development
GO:0001657  ureteric bud development

Cellular Component

GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity