hairy/enhancer-of-split related with YRPW motif 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:114.10 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001058425
Gene ID 155430
Unigene ID Rn.58672
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

1p11  [27,505,182  -  27,513,868]

Gene Family (Interpro ID)

IPR003650  Orange
IPR018352  Orange subgroup

Link to Pubmed  (Pubmed ID)

10692439
11741889
16151017
16953280
17586813

Gene Ontology  (GO ID)

Biological Process

GO:0009948  anterior/posterior axis specification
GO:0060842  arterial endothelial cell differentiation
GO:0060840  artery development
GO:0060413  atrial septum morphogenesis
GO:0003171  atrioventricular valve development
GO:0001568  blood vessel development
GO:0060317  cardiac epithelial to mesenchymal transition
GO:0003214  cardiac left ventricle morphogenesis
GO:0003300  cardiac muscle hypertrophy
GO:0014898  cardiac muscle hypertrophy in response to stress
GO:0003215  cardiac right ventricle morphogenesis
GO:0060411  cardiac septum morphogenesis
GO:0060948  cardiac vascular smooth muscle cell development
GO:0003208  cardiac ventricle morphogenesis
GO:0045165  cell fate commitment
GO:0090102  cochlea development
GO:0060977  coronary vasculature morphogenesis
GO:0003199  endocardial cushion to mesenchymal transition involved in valve formation
GO:0007507  heart development
GO:0060347  heart trabecula formation
GO:0060716  labyrinthine layer blood vessel development
GO:0014031  mesenchymal cell development
GO:0003150  muscular septum morphogenesis
GO:0010667  negative regulation of cardiac muscle cell apoptosis
GO:0010629  negative regulation of gene expression
GO:0045746  negative regulation of Notch signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0060633  negative regulation of transcription initiation from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007219  Notch signaling pathway
GO:0003151  outflow tract morphogenesis
GO:0007389  pattern specification process
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0010460  positive regulation of heart rate
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0065004  protein-DNA complex assembly
GO:0003184  pulmonary valve morphogenesis
GO:0045607  regulation of auditory receptor cell differentiation
GO:0010468  regulation of gene expression
GO:0003195  tricuspid valve formation
GO:0003186  tricuspid valve morphogenesis
GO:0001570  vasculogenesis
GO:0055015  ventricular cardiac muscle cell development
GO:0060412  ventricular septum morphogenesis
GO:0003222  ventricular trabecular myocardium morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0016580  Sin3 complex
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003677  DNA binding
GO:0042826  histone deacetylase binding
GO:0003674  molecular_function
GO:0046983  protein dimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding