DAB2 interacting protein

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:95.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:36.90 spine:- retina:- eye:35.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:318.60 prostate:227.70 ovary:- testis:82.30 heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:101.30    bladder:- kidney:- pituitary:118.40 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_138710
Gene ID 192126
Unigene ID Rn.14323
Probe set ID -
Ensembl ID ENSRNOG00000019237

Orthologous Gene

Human[2]  NM_032552, NM_138709
Mouse[3]  NM_001001602, NM_001114124, NM_001114125

Chromosomal Region

3p11  [14,667,700  -  14,840,623]

Gene Family (Interpro ID)

IPR000008  C2 calcium-dependent membrane targeting
IPR008973  C2 calcium/lipid-binding domain, CaLB
IPR001849  Pleckstrin homology
IPR001936  Ras GTPase-activating protein
IPR008936  Rho GTPase activation protein

Link to Pubmed  (Pubmed ID)

8889548
11812785
12477932
21890121

Gene Ontology  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0000185  activation of MAPKKK activity
GO:0001525  angiogenesis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0007049  cell cycle
GO:0021814  cell motility involved in cerebral cortex radial glia guided migration
GO:0044257  cellular protein catabolic process
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071347  cellular response to interleukin-1
GO:0071222  cellular response to lipopolysaccharide
GO:0071356  cellular response to tumor necrosis factor
GO:0007252  I-kappaB phosphorylation
GO:0008625  induction of apoptosis via death domain receptors
GO:0021819  layer formation in the cerebral cortex
GO:0016525  negative regulation of angiogenesis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010596  negative regulation of endothelial cell migration
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0010633  negative regulation of epithelial cell migration
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0048147  negative regulation of fibroblast proliferation
GO:0070317  negative regulation of G0 to G1 transition
GO:0034260  negative regulation of GTPase activity
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043407  negative regulation of MAP kinase activity
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0043553  negative regulation of phosphoinositide 3-kinase activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0034261  negative regulation of Ras GTPase activity
GO:0046580  negative regulation of Ras protein signal transduction
GO:0034144  negative regulation of toll-like receptor 4 signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030948  negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0048812  neuron projection morphogenesis
GO:0043065  positive regulation of apoptosis
GO:0071158  positive regulation of cell cycle arrest
GO:0050679  positive regulation of epithelial cell proliferation
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0010976  positive regulation of neuron projection development
GO:0045732  positive regulation of protein catabolic process
GO:0032320  positive regulation of Ras GTPase activity
GO:0090129  positive regulation of synapse maturation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032312  regulation of ARF GTPase activity
GO:0043122  regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043254  regulation of protein complex assembly
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0006986  response to unfolded protein
GO:0007165  signal transduction
GO:0035148  tube lumen formation

Cellular Component

GO:0030424  axon
GO:0043025  cell soma
GO:0032809  cell soma membrane
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0030139  endocytic vesicle
GO:0005622  intracellular
GO:0031235  intrinsic to internal side of plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005123  death receptor binding
GO:0005096  GTPase activator activity
GO:0042802  identical protein binding
GO:0019900  kinase binding
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0032266  phosphatidylinositol 3-phosphate binding
GO:0070273  phosphatidylinositol-4-phosphate binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0047485  protein N-terminus binding
GO:0051721  protein phosphatase 2A binding
GO:0005099  Ras GTPase activator activity
GO:0017124  SH3 domain binding
GO:0043184  vascular endothelial growth factor receptor 2 binding