adenosine deaminase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:860.40 bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:199.10 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:418.70 colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_130399
Gene ID 24165
Unigene ID Rn.12689
Probe set ID -
Ensembl ID ENSRNOG00000010265

Orthologous Gene

Human[2]  NM_000022
Mouse[1]  NM_007398

Chromosomal Region

3q42  [154,636,532  -  154,660,637]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2253038
2982653
3746429
4462574
6815190
8227344
9255891
9478961
9605386
9784839
10410539
11038259
11125071
11683239
12194640
12472193
12477932
12597017
12675911
15168879
15489334
15966013
15969953
16501670
16563876
16641873
16716042
16754522
16860713
17259686
17942570
18561952
19066225
19166862
19559780
19900420
19934879
20228181
20735412
20809996
21161045
21320715

Gene Ontology  (GO ID)

Biological Process

GO:0006154  adenosine catabolic process
GO:0046085  adenosine metabolic process
GO:0007568  aging
GO:0007155  cell adhesion
GO:0046061  dATP catabolic process
GO:0006157  deoxyadenosine catabolic process
GO:0048566  embryonic gut development
GO:0002314  germinal center B cell differentiation
GO:0001821  histamine secretion
GO:0046101  hypoxanthine biosynthetic process
GO:0043103  hypoxanthine salvage
GO:0001701  in utero embryonic development
GO:0046103  inosine biosynthetic process
GO:0001889  liver development
GO:0048286  lung alveolus development
GO:0030324  lung development
GO:0060169  negative regulation of adenosine receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0042323  negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0050728  negative regulation of inflammatory response
GO:0002686  negative regulation of leukocyte migration
GO:0002906  negative regulation of mature B cell apoptosis
GO:0070256  negative regulation of mucus secretion
GO:0060407  negative regulation of penile erection
GO:0070244  negative regulation of thymocyte apoptosis
GO:0048541  Peyer's patch development
GO:0001890  placenta development
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0030890  positive regulation of B cell proliferation
GO:0050850  positive regulation of calcium-mediated signaling
GO:0002636  positive regulation of germinal center formation
GO:0010460  positive regulation of heart rate
GO:0045987  positive regulation of smooth muscle contraction
GO:0050870  positive regulation of T cell activation
GO:0045582  positive regulation of T cell differentiation
GO:0033089  positive regulation of T cell differentiation in the thymus
GO:0050862  positive regulation of T cell receptor signaling pathway
GO:0032261  purine nucleotide salvage
GO:0009168  purine ribonucleoside monophosphate biosynthetic process
GO:0033632  regulation of cell-cell adhesion mediated by integrin
GO:0045187  regulation of circadian sleep/wake cycle, sleep
GO:0045580  regulation of T cell differentiation
GO:0042493  response to drug
GO:0042542  response to hydrogen peroxide
GO:0001666  response to hypoxia
GO:0043278  response to morphine
GO:0033197  response to vitamin E
GO:0042110  T cell activation
GO:0001829  trophectodermal cell differentiation
GO:0046111  xanthine biosynthetic process

Cellular Component

GO:0030054  cell junction
GO:0043025  cell soma
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0060205  cytoplasmic membrane-bounded vesicle lumen
GO:0005829  cytosol
GO:0032839  dendrite cytoplasm
GO:0009897  external side of plasma membrane
GO:0005615  extracellular space
GO:0005764  lysosome
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004000  adenosine deaminase activity
GO:0001883  purine nucleoside binding
GO:0008270  zinc ion binding