insulin-like growth factor 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:346.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:71.10 artery/aorta:1071.40 vein:- lymphnode:- peripheral blood:- spleen:624 thymus:- bone marrow:- adipose:147.20 bone:390.50 skin:-
GeneChip cerebrum:7.52 cerebellum:7.63 brain stem:7.43 corpus callosum/glia:- pineal gland:- peripheral nerve:7.46 spine:- retina:- eye:7.53 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.14 thymus:7.13 bone marrow:7.37 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:2668.30 prostate:75.90 ovary:114.10 testis:- heart:1027.60 muscle:- esophagus:- stomach:- intestine:314 colon:-     liver/hepato:265.90        lung:304    bladder:- kidney:510.50 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.43 muscle:7.86 esophagus:- stomach:- intestine:7.16 colon:6.94 liver/hepato:- lung:- bladder:- kidney:7.21 pituitary:6.99 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_031511
Gene ID 24483
Unigene ID Rn.118681
Probe set ID E00988mRNA_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000020369

Orthologous Gene

Human[18]  NM_000612, NM_001007139, NM_001127598
Mouse[6]  NM_001122736, NM_001122737, NM_010514

Chromosomal Region

1q41  [202,906,624  -  202,915,231]

Gene Family (Interpro ID)

IPR016179  Insulin-like
IPR004825  Insulin/IGF/relaxin

Link to Pubmed  (Pubmed ID)

2322575
2383591
2438416
2477062
2538475
2974285
3023383
3167060
3221878
3453119
3889836
6382022
6390212
7016879
7521338
7770004
8609235
8764603
9160836
9199194
9336345
9336384
9685318
10417663
10686593
10727441
11123717
11213353
11232005
11247331
11307180
11448941
12006713
12532445
12548059
12719647
12927688
15833775
15862547
16088202
16448778
16477536
16627931
16787587
16825605
17023532
17184497
17393425
17407073
17476475
17554210
17556377
17626604
17628003
17630476
17724018
18418699
18421211
18478565
18505416
18676006
18693177
18719053
18724775
18778817
18946176
19494366
19556211
19592596
19648158
19683557
19764351
19776249
19919529
20671425
20683203
20683839
20695079
21270887
21598309
21613208
21859454
21959847
22434232
23016131
23016132
23229416

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0071260  cellular response to mechanical stimulus
GO:0031017  exocrine pancreas development
GO:0007565  female pregnancy
GO:0006006  glucose metabolic process
GO:0007613  memory
GO:0009887  organ morphogenesis
GO:0001649  osteoblast differentiation
GO:0042104  positive regulation of activated T cell proliferation
GO:0043085  positive regulation of catalytic activity
GO:0051781  positive regulation of cell division
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0046628  positive regulation of insulin receptor signaling pathway
GO:0043410  positive regulation of MAPKKK cascade
GO:0045840  positive regulation of mitosis
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0090031  positive regulation of steroid hormone biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0045471  response to ethanol
GO:0035094  response to nicotine
GO:0031667  response to nutrient levels
GO:0014070  response to organic cyclic substance
GO:0009314  response to radiation
GO:0051146  striated muscle cell differentiation
GO:0042060  wound healing

Cellular Component

GO:0005615  extracellular space

Molecular Function

GO:0008083  growth factor activity
GO:0005179  hormone activity
GO:0005158  insulin receptor binding
GO:0005159  insulin-like growth factor receptor binding
GO:0005515  protein binding
GO:0043539  protein serine/threonine kinase activator activity
GO:0030546  receptor activator activity