platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:119.50 prostate:- ovary:- testis:- heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001075973
Gene ID 24628
Unigene ID Rn.198230
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

7q34  [118,244,386  -  118,262,021]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1708827
7758166
8094359
8318539
8447423
8504434
8644858
8889548
10550325
10802145
11005132
11780721
11903042
11967988
11994382
11997247
12084843
12171932
12533868
12606528
12641779
12753322
12819032
14685146
14711826
14724432
14751865
14980813
15021824
15067514
15681847
16014047
16019429
16039137
16156274
16294022
16368696
16596190
16893901
16971352
16990553
17134509
17195235
17442164
17449016
17519529
17533428
17654489
17674348
17893914
18180311
18483410
18723570
18775895
19133316
19426591
19442606
19460854
19691150
19880494
20307544
20452974
20718713
20860549
21092652
21158157
21211989
21216974
21245329
21255638
21351537
21367419
21368226
21435466
21451101
21568693
21750433
21792920
21803557
21819559
21868503
22407906
22488213
22523431
22539040
23103565
23179587
23298764
23460471
24100802
24472833

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0032147  activation of protein kinase activity
GO:0032148  activation of protein kinase B activity
GO:0007596  blood coagulation
GO:0048514  blood vessel morphogenesis
GO:0060445  branching involved in salivary gland morphogenesis
GO:0060326  cell chemotaxis
GO:0016049  cell growth
GO:0030031  cell projection assembly
GO:0071363  cellular response to growth factor stimulus
GO:0071506  cellular response to mycophenolic acid
GO:0006260  DNA replication
GO:0001892  embryonic placenta development
GO:0060664  epithelial cell proliferation involved in salivary gland morphogenesis
GO:0007507  heart development
GO:0030097  hemopoiesis
GO:0002548  monocyte chemotaxis
GO:0030336  negative regulation of cell migration
GO:0010512  negative regulation of phosphatidylinositol biosynthetic process
GO:0010544  negative regulation of platelet activation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0018105  peptidyl-serine phosphorylation
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0050918  positive chemotaxis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0051781  positive regulation of cell division
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0050921  positive regulation of chemotaxis
GO:0045737  positive regulation of cyclin-dependent protein kinase activity
GO:0045740  positive regulation of DNA replication
GO:0001938  positive regulation of endothelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0045743  positive regulation of fibroblast growth factor receptor signaling pathway
GO:0048146  positive regulation of fibroblast proliferation
GO:0003104  positive regulation of glomerular filtration
GO:0043406  positive regulation of MAP kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0045840  positive regulation of mitosis
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0031954  positive regulation of protein amino acid autophosphorylation
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006468  protein amino acid phosphorylation
GO:0042127  regulation of cell proliferation
GO:0050730  regulation of peptidyl-tyrosine phosphorylation
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0043627  response to estrogen stimulus
GO:0001666  response to hypoxia
GO:0032868  response to insulin stimulus
GO:0014070  response to organic cyclic substance
GO:0010033  response to organic substance
GO:0009611  response to wounding
GO:0006929  substrate-bound cell migration
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0042060  wound healing

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0016020  membrane

Molecular Function

GO:0042056  chemoattractant activity
GO:0005518  collagen binding
GO:0008083  growth factor activity
GO:0048407  platelet-derived growth factor binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0016176  superoxide-generating NADPH oxidase activator activity