neurotrophic tyrosine kinase, receptor, type 2

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Synonym

normal 40 tissues
data not exists

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:335

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:147.50

spine:-

retina:-

eye:106.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:312

thymus:-

bone marrow:-

adipose:441.60

bone:-

skin:-

GeneChip

cerebrum:7.54

cerebellum:7.44

brain stem:7.69

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.81

spine:-

retina:-

eye:6.06

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:5.93

thymus:5.97

bone marrow:6.09

adipose:-

bone:-

skin:-

CAGE

nodata

RNA-seq

nodata

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:39.80

prostate:38

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:296.10

thyroid/parathyroid:-

adrenal gland:-

pancreas:56.90

breast:-

salivary:-

GeneChip

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:5.77

muscle:6.07

esophagus:-

stomach:-

intestine:5.69

colon:5.91

liver/hepato:-

lung:-

bladder:-

kidney:5.88

pituitary:6.27

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

CAGE

nodata

RNA-seq

nodata

IDs

Refseq ID	NM_001163169
Gene ID	25054
Unigene ID	Rn.11246
Probe set ID	M55291_at [RG_U34A]
Ensembl ID	ENSRNOG00000018839

Orthologous Gene

Human[14]	NM_001007097, NM_001018064, NM_001018065, NM_001018066, NM_006180
Mouse[3]	NM_001025074, NM_008745, NM_001018065, NM_001018066, NM_006180

Chromosomal Region

17p14 [11,494,463 - 11,811,654]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007568	aging
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway
GO:0021954	central nervous system neuron development
GO:0021987	cerebral cortex development
GO:0007631	feeding behavior
GO:0014047	glutamate secretion
GO:0007612	learning
GO:0007616	long-term memory
GO:0060291	long-term synaptic potentiation
GO:0042490	mechanoreceptor differentiation
GO:0043524	negative regulation of neuron apoptosis
GO:0007528	neuromuscular junction development
GO:0030182	neuron differentiation
GO:0001764	neuron migration
GO:0048709	oligodendrocyte differentiation
GO:0048935	peripheral nervous system neuron development
GO:0050772	positive regulation of axonogenesis
GO:0008284	positive regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0043410	positive regulation of MAPKKK cascade
GO:0010976	positive regulation of neuron projection development
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0051968	positive regulation of synaptic transmission, glutamatergic
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0050773	regulation of dendrite development
GO:0043408	regulation of MAPKKK cascade
GO:0019222	regulation of metabolic process
GO:0046928	regulation of neurotransmitter secretion
GO:0051896	regulation of protein kinase B signaling cascade
GO:0032314	regulation of Rac GTPase activity
GO:0010996	response to auditory stimulus
GO:0046548	retinal rod cell development
GO:0001570	vasculogenesis

Cellular Component

GO:0030424	axon
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005829	cytosol
GO:0030425	dendrite
GO:0043197	dendritic spine
GO:0010008	endosome membrane
GO:0060076	excitatory synapse
GO:0000139	Golgi membrane
GO:0030426	growth cone
GO:0005887	integral to plasma membrane
GO:0005622	intracellular
GO:0043679	nerve terminal
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane
GO:0048786	presynaptic active zone
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0048403	brain-derived neurotrophic factor binding
GO:0060175	brain-derived neurotrophic factor receptor activity
GO:0046875	ephrin receptor binding
GO:0043121	neurotrophin binding
GO:0005030	neurotrophin receptor activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004714	transmembrane receptor protein tyrosine kinase activity

IPR000276	7TM GPCR, rhodopsin-like
IPR002131	Glycoprotein hormone receptor
IPR017452	GPCR, rhodopsin-like superfamily
IPR002273	Lutropin-choriogonadotropic hormone receptor
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

neurotrophic tyrosine kinase, receptor, type 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function