cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:8.04 cerebellum:8 brain stem:8.31 corpus callosum/glia:- pineal gland:- peripheral nerve:7.81 spine:- retina:- eye:8.37 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:7.82 thymus:7.46 bone marrow:7.51 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:372.30        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:8.42 muscle:7.59 esophagus:- stomach:- intestine:7.53 colon:7.29 liver/hepato:- lung:- bladder:- kidney:7.65 pituitary:7.31 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013105
Gene ID 25642
Unigene ID Rn.91120
Probe set ID X62086mRNA_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000032560

Orthologous Gene

Human[19]  NM_022820, NM_057095, NM_057096, NM_000777, NM_001190484, NM_001202855, NM_017460, NM_000765
Mouse[9]  NM_019792, NM_007819, NM_007820, NM_177380, NM_007818, NM_001105160, NM_001100180, NM_017396, NM_001105159

Chromosomal Region

12p11  [9,566,781  -  9,595,971]

Gene Family (Interpro ID)

IPR001128  Cytochrome P450
IPR002397  Cytochrome P450, B-class
IPR008072  Cytochrome P450, E-class, CYP3A
IPR002401  Cytochrome P450, E-class, group I
IPR002402  Cytochrome P450, E-class, group II
IPR002403  Cytochrome P450, E-class, group IV

Link to Pubmed  (Pubmed ID)

1298226
1372436
1417000
1731631
2398038
3838989
3875783
7528203
7681660
8274011
8841512
9989933
11901229
12167482
12477932
12971802
14595535
15060019
15349958
15771231
15979568
16039771
16207635
16380645
16461430
17484520
18057719
19435144
19504095
19848203
20599767
22159698
22822673
23762486

Gene Ontology  (GO ID)

Biological Process

GO:0007568  aging
GO:0009822  alkaloid catabolic process
GO:0042737  drug catabolic process
GO:0017144  drug metabolic process
GO:0070989  oxidative demethylation
GO:0046686  response to cadmium ion
GO:0042493  response to drug
GO:0051384  response to glucocorticoid stimulus
GO:0010038  response to metal ion
GO:0007584  response to nutrient

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0043231  intracellular membrane-bounded organelle

Molecular Function

GO:0070330  aromatase activity
GO:0032451  demethylase activity
GO:0009055  electron carrier activity
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0016491  oxidoreductase activity
GO:0016712  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0050649  testosterone 6-beta-hydroxylase activity