zinc finger E-box binding homeobox 1

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:83.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:73.70 spine:- retina:- eye:142.20 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:294.40 bone:- skin:-
GeneChip cerebrum:5.70 cerebellum:5.65 brain stem:5.66 corpus callosum/glia:- pineal gland:- peripheral nerve:5.47 spine:- retina:- eye:5.45 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.65 thymus:5.66 bone marrow:5.93 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:79.60 prostate:38 ovary:114.10 testis:- heart:58.20 muscle:- esophagus:- stomach:- intestine:- colon:289.90     liver/hepato:26.60        lung:-    bladder:- kidney:255.20 pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:5.89 muscle:5.86 esophagus:- stomach:- intestine:5.37 colon:5.32 liver/hepato:- lung:- bladder:- kidney:5.71 pituitary:5.23 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_013164
Gene ID 25705
Unigene ID Rn.106000
Probe set ID U51583_at  [RG_U34A]
Ensembl ID ENSRNOG00000017863

Orthologous Gene

Human[6]  NM_001128128, NM_001174093, NM_001174094, NM_001174095, NM_001174096, NM_030751
Mouse[1]  NM_011546, NM_001174093, NM_001174094, NM_001174095, NM_001174096, NM_030751

Chromosomal Region

17q12.1  [60,177,064  -  60,234,473]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related
IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

8769566
11476947
11731009
12193549
14672405
15226419
16824956
19194497
19366873
20705680
20856809
21478908
22012804

Gene Ontology  (GO ID)

Biological Process

GO:0051216  cartilage development
GO:0071230  cellular response to amino acid stimulus
GO:0007417  central nervous system development
GO:0090103  cochlea morphogenesis
GO:0048596  embryonic camera-type eye morphogenesis
GO:0048598  embryonic morphogenesis
GO:0048704  embryonic skeletal system morphogenesis
GO:0030900  forebrain development
GO:0008285  negative regulation of cell proliferation
GO:0030857  negative regulation of epithelial cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0048513  organ development
GO:0007389  pattern specification process
GO:0045666  positive regulation of neuron differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010464  regulation of mesenchymal cell proliferation
GO:0051150  regulation of smooth muscle cell differentiation
GO:0033081  regulation of T cell differentiation in the thymus
GO:0017015  regulation of transforming growth factor beta receptor signaling pathway
GO:0014823  response to activity
GO:0031667  response to nutrient levels
GO:0048752  semicircular canal morphogenesis
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003690  double-stranded DNA binding
GO:0070888  E-box binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0008270  zinc ion binding