nucleoside phosphorylase

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:119.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:258.10 spine:- retina:- eye:71.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:1092 thymus:245.80 bone marrow:- adipose:588.80 bone:117.10 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1139 placenta:159.30 prostate:151.80 ovary:570.60 testis:- heart:213.30 muscle:265.70 esophagus:- stomach:- intestine:314 colon:289.90     liver/hepato:199.50        lung:253.30    bladder:- kidney:319 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_214155
Gene ID 290029
Unigene ID Rn.2738
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

15p14  [26,929,784  -  26,937,434]

Gene Family (Interpro ID)

IPR011268  Inosine guanosine/xanthosine phosphorylase
IPR000845  Nucleoside phosphorylase
IPR011270  Purine nucleoside phosphorylase I, inosine/guanosine-specific
IPR001369  Purine phosphorylase, family 2

Link to Pubmed  (Pubmed ID)

1834379
2120328
3029074
15532538

Gene Ontology  (GO ID)

Biological Process

GO:0008637  apoptotic mitochondrial changes
GO:0006161  deoxyguanosine catabolic process
GO:0006149  deoxyinosine catabolic process
GO:0046070  dGTP metabolic process
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0006183  GTP biosynthetic process
GO:0046115  guanosine catabolic process
GO:0006955  immune response
GO:0006148  inosine catabolic process
GO:0070970  interleukin-2 secretion
GO:0034356  NAD biosynthesis via nicotinamide riboside salvage pathway
GO:0070233  negative regulation of T cell apoptosis
GO:0006738  nicotinamide riboside catabolic process
GO:0006139  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0009116  nucleoside metabolic process
GO:0046638  positive regulation of alpha-beta T cell differentiation
GO:0045579  positive regulation of B cell differentiation
GO:0045739  positive regulation of DNA repair
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0042102  positive regulation of T cell proliferation
GO:0042278  purine nucleoside metabolic process
GO:0043101  purine salvage
GO:0042493  response to drug
GO:0010332  response to gamma radiation
GO:0034418  urate biosynthetic process

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005622  intracellular
GO:0005634  nucleus

Molecular Function

GO:0008144  drug binding
GO:0001882  nucleoside binding
GO:0042301  phosphate binding
GO:0002060  purine binding
GO:0004731  purine-nucleoside phosphorylase activity