ADAM metallopeptidase domain 9 (meltrin gamma)

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:47.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:147.20 bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:114.10 testis:82.30 heart:19.40 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:304    bladder:- kidney:127.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001014772
Gene ID 290834
Unigene ID Rn.25221
Probe set ID -
Ensembl ID ENSRNOG00000017231

Orthologous Gene

Human[1]  NM_003816
Mouse[1]  NM_007404

Chromosomal Region

16q12.4  [71,446,498  -  71,526,108]

Gene Family (Interpro ID)

IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

8889548
10752518
11156854
14997207
15688065
15950787
17465204
19473694

Gene Ontology  (GO ID)

Biological Process

GO:0000186  activation of MAPKK activity
GO:0007155  cell adhesion
GO:0033627  cell adhesion mediated by integrin
GO:0033631  cell-cell adhesion mediated by integrin
GO:0007160  cell-matrix adhesion
GO:0071222  cellular response to lipopolysaccharide
GO:0030216  keratinocyte differentiation
GO:0006509  membrane protein ectodomain proteolysis
GO:0042117  monocyte activation
GO:0051088  PMA-inducible membrane protein ectodomain proteolysis
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0051549  positive regulation of keratinocyte migration
GO:0034241  positive regulation of macrophage fusion
GO:0051044  positive regulation of membrane protein ectodomain proteolysis
GO:0050714  positive regulation of protein secretion
GO:0006508  proteolysis
GO:0051592  response to calcium ion
GO:0051384  response to glucocorticoid stimulus
GO:0042542  response to hydrogen peroxide
GO:0034616  response to laminar fluid shear stress
GO:0010042  response to manganese ion
GO:0034612  response to tumor necrosis factor
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0031233  intrinsic to external side of plasma membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005518  collagen binding
GO:0005178  integrin binding
GO:0043236  laminin binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0003674  molecular_function
GO:0005080  protein kinase C binding
GO:0017124  SH3 domain binding
GO:0008270  zinc ion binding