axin2

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:106.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.97 cerebellum:5.88 brain stem:5.86 corpus callosum/glia:- pineal gland:- peripheral nerve:5.91 spine:- retina:- eye:5.65 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:5.90 thymus:6.28 bone marrow:6.25 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:1129.90 kidney:63.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:6 muscle:6.10 esophagus:- stomach:- intestine:6.02 colon:6.25 liver/hepato:- lung:- bladder:- kidney:5.99 pituitary:6.12 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_024355
Gene ID 29134
Unigene ID Rn.162212
Probe set ID AF017757_at  [RG_U34A]
Ensembl ID ENSRNOG00000003612

Orthologous Gene

Human[1]  NM_004655
Mouse[2]  NM_015732

Chromosomal Region

10q32.1  [98,294,466  -  98,321,824]

Gene Family (Interpro ID)

IPR000342  Regulator of G protein signalling
IPR016137  Regulator of G protein signalling superfamily

Link to Pubmed  (Pubmed ID)

9566905
15572025
16488995
18432252
19464575
22152883

Gene Ontology  (GO ID)

Biological Process

GO:0030282  bone mineralization
GO:0008219  cell death
GO:0008283  cell proliferation
GO:0034613  cellular protein localization
GO:0071407  cellular response to organic cyclic substance
GO:0003413  chondrocyte differentiation involved in endochondral bone morphogenesis
GO:0001957  intramembranous ossification
GO:0043570  maintenance of DNA repeat elements
GO:0048255  mRNA stabilization
GO:0008285  negative regulation of cell proliferation
GO:0045668  negative regulation of osteoblast differentiation
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0042476  odontogenesis
GO:0010942  positive regulation of cell death
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0043547  positive regulation of GTPase activity
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0070602  regulation of centromeric sister chromatid cohesion
GO:0032423  regulation of mismatch repair
GO:0030111  regulation of Wnt receptor signaling pathway
GO:0001756  somitogenesis

Cellular Component

GO:0005938  cell cortex
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005881  cytoplasmic microtubule
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0043234  protein complex

Molecular Function

GO:0070016  armadillo repeat domain binding
GO:0008013  beta-catenin binding
GO:0019899  enzyme binding
GO:0005096  GTPase activator activity
GO:0070411  I-SMAD binding
GO:0019901  protein kinase binding
GO:0004871  signal transducer activity
GO:0031625  ubiquitin protein ligase binding