excision repair cross-complementing rodent repair deficiency, complementation group 1

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Synonym

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Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:106.60 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:235.40
GeneChip cerebrum:8.18 cerebellum:8.09 brain stem:8.05 corpus callosum/glia:- pineal gland:- peripheral nerve:8.20 spine:- retina:- eye:8.26 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:8.09 thymus:8 bone marrow:8.20 adipose:- bone:- skin:-
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:- ovary:- testis:- heart:77.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:13.30        lung:-    bladder:- kidney:- pituitary:59.20 thyroid/parathyroid:- adrenal gland:- pancreas:56.90 breast:- salivary:-
GeneChip uterus:- placenta:- prostate:- ovary:- testis:- heart:7.97 muscle:8.07 esophagus:- stomach:- intestine:7.85 colon:7.85 liver/hepato:- lung:- bladder:- kidney:7.99 pituitary:8.01 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001106228
Gene ID 292673
Unigene ID Rn.7320
Probe set ID rc_AA892791_at  [RG_U34A]
Ensembl ID ENSRNOG00000017839

Orthologous Gene

Human[5]  NM_001166049, NM_001983, NM_202001
Mouse[2]  NM_001127324, NM_007948, NM_202001

Chromosomal Region

1q21  [78,711,249  -  78,722,474]

Gene Family (Interpro ID)

IPR003583  Helix-hairpin-helix DNA-binding motif, class 1
IPR000445  Helix-hairpin-helix motif

Link to Pubmed  (Pubmed ID)

11425516
12919963
14670002
15145517
19154342
19440222

Gene Ontology  (GO ID)

Biological Process

GO:0048468  cell development
GO:0008283  cell proliferation
GO:0051276  chromosome organization
GO:0006310  DNA recombination
GO:0006281  DNA repair
GO:0006302  double-strand break repair
GO:0048568  embryonic organ development
GO:0007281  germ cell development
GO:0045190  isotype switching
GO:0008584  male gonad development
GO:0006312  mitotic recombination
GO:0035264  multicellular organism growth
GO:0010259  multicellular organismal aging
GO:0043066  negative regulation of apoptosis
GO:0032205  negative regulation of telomere maintenance
GO:0006289  nucleotide-excision repair
GO:0006295  nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296  nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0048477  oogenesis
GO:0035166  post-embryonic hemopoiesis
GO:0000720  pyrimidine dimer repair by nucleotide-excision repair
GO:0001302  replicative cell aging
GO:0009628  response to abiotic stimulus
GO:0006974  response to DNA damage stimulus
GO:0007584  response to nutrient
GO:0006979  response to oxidative stress
GO:0009744  response to sucrose stimulus
GO:0010165  response to X-ray
GO:0007283  spermatogenesis
GO:0006949  syncytium formation
GO:0009650  UV protection

Cellular Component

GO:0005737  cytoplasm
GO:0000784  nuclear chromosome, telomeric region
GO:0005730  nucleolus
GO:0000109  nucleotide-excision repair complex
GO:0005634  nucleus
GO:0005669  transcription factor TFIID complex

Molecular Function

GO:0003684  damaged DNA binding
GO:0003674  molecular_function
GO:0008022  protein C-terminus binding
GO:0019904  protein domain specific binding
GO:0003697  single-stranded DNA binding
GO:0000014  single-stranded DNA specific endodeoxyribonuclease activity
GO:0043566  structure-specific DNA binding
GO:0017025  TATA-binding protein binding