low density lipoprotein receptor-related protein 5

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:78 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001106321
Gene ID 293649
Unigene ID Rn.126980
Probe set ID -
Ensembl ID ENSRNOG00000015911

Orthologous Gene

Human[3]  NM_001135772, NM_182492, NM_002335
Mouse[1]  NM_008513, NM_182492, NM_002335

Chromosomal Region

1q42  [206,102,753  -  206,206,350]

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3
IPR001258  NHL repeat

Link to Pubmed  (Pubmed ID)

12477932
15346351
15923619
15962290
17002564
17229572
18089564
18432252
19047013
20042609
23481549

Gene Ontology  (GO ID)

Biological Process

GO:0060612  adipose tissue development
GO:0060033  anatomical structure regression
GO:0009952  anterior/posterior pattern formation
GO:0060348  bone development
GO:0048539  bone marrow development
GO:0060349  bone morphogenesis
GO:0046849  bone remodeling
GO:0060444  branching involved in mammary gland duct morphogenesis
GO:0042074  cell migration involved in gastrulation
GO:0060764  cell-cell signaling involved in mammary gland development
GO:0042632  cholesterol homeostasis
GO:0008203  cholesterol metabolic process
GO:0048596  embryonic camera-type eye morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0030326  embryonic limb morphogenesis
GO:0060059  embryonic retina morphogenesis in camera-type eye
GO:0001702  gastrulation with mouth forming second
GO:0006007  glucose catabolic process
GO:0006917  induction of apoptosis
GO:0035108  limb morphogenesis
GO:0060603  mammary gland duct morphogenesis
GO:0045668  negative regulation of osteoblast differentiation
GO:0002076  osteoblast development
GO:0008284  positive regulation of cell proliferation
GO:0045600  positive regulation of fat cell differentiation
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045840  positive regulation of mitosis
GO:0033690  positive regulation of osteoblast proliferation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0042981  regulation of apoptosis
GO:0008217  regulation of blood pressure
GO:0046850  regulation of bone remodeling
GO:0045598  regulation of fat cell differentiation
GO:0030278  regulation of ossification
GO:0060828  regulation of Wnt receptor signaling pathway through beta-catenin
GO:0043434  response to peptide hormone stimulus
GO:0060042  retina morphogenesis in camera-type eye
GO:0035019  somatic stem cell maintenance
GO:0001944  vasculature development
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005575  cellular_component
GO:0016021  integral to membrane
GO:0005739  mitochondrion
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0015026  coreceptor activity
GO:0003674  molecular_function
GO:0019534  toxin transporter activity
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding