sterol regulatory element binding transcription factor 2

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:131.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:147.50 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:39 skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:379.60 ovary:- testis:- heart:155.10 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:177.70 thyroid/parathyroid:- adrenal gland:- pancreas:113.80 breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001033694
Gene ID 300095
Unigene ID Rn.41063
Probe set ID -
Ensembl ID ENSRNOG00000007400

Orthologous Gene

Human[2]  NM_004599
Mouse[2]  NM_033218

Chromosomal Region

7q34  [120,522,511  -  120,580,210]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1581819
9786926
10600799
11278421
11551527
11950857
12421847
12446768
12477932
12488438
12801623
15026365
15062879
15547298
15644403
15944339
16046298
16055439
16082694
16316337
16705668
16723505
16741953
16814791
16936198
16941710
17524234
17526932
17572141
17709436
17884448
18095312
18682608
19124072
19147991
19470373
19808779
19933148
21726644
22713868
23263379
23542164
24068000

Gene Ontology  (GO ID)

Biological Process

GO:0007568  aging
GO:0008203  cholesterol metabolic process
GO:0008610  lipid biosynthetic process
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0010886  positive regulation of cholesterol storage
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006355  regulation of transcription, DNA-dependent
GO:0042493  response to drug
GO:0009725  response to hormone stimulus
GO:0010288  response to lead ion
GO:0033993  response to lipid
GO:0055098  response to low-density lipoprotein stimulus
GO:0007283  spermatogenesis
GO:0032933  SREBP-mediated signaling pathway
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0012507  ER to Golgi transport vesicle membrane
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005634  nucleus
GO:0032937  SREBP-SCAP-Insig complex

Molecular Function

GO:0000247  C-8 sterol isomerase activity
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0070888  E-box binding
GO:0008022  protein C-terminus binding
GO:0046983  protein dimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity