receptor-interacting serine-threonine kinase 2

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:39.80 prostate:75.90 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

Gene Information

IDs

Refseq ID XM_001056736
Gene ID 362491
Unigene ID Rn.102179
Probe set ID -
Ensembl ID -

Orthologous Gene

Human [0]  
Mouse [0]  

Chromosomal Region

5q13  [30,714,817  -  30,745,807]

Gene Family (Interpro ID)

IPR001315  Caspase Recruitment
IPR011029  DEATH-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

12477932

Gene Ontology  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0071222  cellular response to lipopolysaccharide
GO:0071223  cellular response to lipoteichoic acid
GO:0071224  cellular response to peptidoglycan
GO:0050830  defense response to Gram-positive bacterium
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0045087  innate immune response
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0070427  nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431  nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0043065  positive regulation of apoptosis
GO:0032722  positive regulation of chemokine production
GO:0001961  positive regulation of cytokine-mediated signaling pathway
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0033091  positive regulation of immature T cell proliferation
GO:0032729  positive regulation of interferon-gamma production
GO:0032743  positive regulation of interleukin-2 production
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0031398  positive regulation of protein ubiquitination
GO:0032874  positive regulation of stress-activated MAPK cascade
GO:0045627  positive regulation of T-helper 1 cell differentiation
GO:0002827  positive regulation of T-helper 1 type immune response
GO:0032760  positive regulation of tumor necrosis factor production
GO:0043281  regulation of caspase activity
GO:0043330  response to exogenous dsRNA
GO:0070555  response to interleukin-1
GO:0070671  response to interleukin-12
GO:0070673  response to interleukin-18
GO:0042098  T cell proliferation
GO:0050852  T cell receptor signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0005524  ATP binding
GO:0050700  CARD domain binding
GO:0030274  LIM domain binding
GO:0042803  protein homodimerization activity
GO:0004674  protein serine/threonine kinase activity